Evidence map›Paper›PMID 41762706›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Beyond CD30: Dual-Targeting of Malignant and Regulatory T Cells by Brentuximab Vedotin Remodels the Lymphoma Microenvironment and Overcomes Resistance via BCL2 Inhibition in Mycosis Fungoides.

Yi Jiang, Pan Lai, Mingjia Li, Yujie Wen, Mengzhou Cao, Yu Xiao, Zhuojing Chen, Jingru Sun, Yang Wang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yi JiangDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Pan LaiDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Mingjia LiDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Yujie WenDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Mengzhou CaoDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Yu XiaoDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Zhuojing ChenDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Jingru SunDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Yang WangDepartment of Dermatology and Venereology, Peking University First Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-7805-2861

Funding

Beijing Natural Science Foundation Z240016Capital's Funds for Health Improvement and Research 2024-1-4074National Natural Science Foundation of China 82002903
6 · The paper itself

Abstract

Mycosis fungoides (MF), the most common subtype of cutaneous T cell lymphoma (CTCL), has a poor prognosis in advanced stages. Brentuximab vedotin (BV), a CD30-targeting antigen-drug conjugate approved for CD30

Indexed as

Brentuximab VedotinKi-1 AntigenMycosis FungoidesProto-Oncogene Proteins c-bcl-2Skin NeoplasmsT-Lymphocytes, RegulatoryTumor MicroenvironmentDrug Resistance, NeoplasmFemaleHumansLymphoma, T-Cell, CutaneousBCL2 protein, humanBrentuximab VedotinKi-1 AntigenProto-Oncogene Proteins c-bcl-2BCL2brentuximab vedotininterferon responsemycosis fungoidestumor microenvironment

Identifiers

PMID41762706
PMCPMC13159111

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.