Evidence map›Paper›PMID 41764596›Full record

ArticleMicrobiome2026

Probiotic efficacy of Bacillus amyloliquefaciens TL106 from Tibetan pigs in metabolic syndrome: modulation of gut microbiota and metabolic in sows and suckling piglets.

Wangyuan Yao, Haitao Du, Md F Kulyar, Huachun Pan, Hongkai Ren, Qingqing Luo, Zeeshan Ahmad Bhutta, Suozhu Liu, Rendong Fang, Jiakui Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiome, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wangyuan YaoCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, P.R. China.
Haitao DuCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, P.R. China.
Md F KulyarDepartment of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, 08406, Lithuania.
Huachun PanCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, P.R. China.
Hongkai RenCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, P.R. China.
Qingqing LuoCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, P.R. China.
Zeeshan Ahmad BhuttaLaboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.
Suozhu LiuCollege of Animals Husbandry and Veterinary Medicine, Tibet Agricultural and Animal Husbandry University, Linzhi, Tibet, 860000, P.R. China.
Rendong FangCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, P.R. China. rdfang@swu.edu.cn.
Jiakui LiCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic syndrome disrupts metabolic resilience in periparturient sows and compromises piglet growth. As intestinal microbes govern host energy homeostasis, microbiome-directed feed additives represent a practical solution. We therefore evaluated the Tibetan‑pig isolate Bacillus amyloliquefaciens TL106, previously validated in weanlings for its capacity to alleviate sow-associated metabolic syndrome.

resultsIn a 43‑day trial (20 sows per group), dietary TL106 (5 × 10

conclusionsBacillus amyloliquefaciens TL106 simultaneously enhanced maternal metabolic health and neonatal development by reshaping gut microbiota and host metabolism, positioning it as a micro‑ecological tool for managing metabolic syndrome in Landrace × Yorkshire sows and Duroc × Landrace × Yorkshire suckling piglets. Video Abstract.

Indexed as

Bacillus amyloliquefaciensGastrointestinal MicrobiomeMetabolic SyndromeProbioticsAnimal FeedAnimalsAnimals, SucklingCecumFemaleInterleukin-1betaSwineTibetTumor Necrosis Factor-alphaInterleukin-1betaTumor Necrosis Factor-alphaBacillus amyloliquefaciens TL106Growth performanceGut microbeMetabolic syndromeSowSuckling piglet

Identifiers

PMID41764596
PMCPMC13001277

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.