ArticleThe Journal of steroid biochemistry and molecular biology2026
Structure-activity relationships of steroid and sterol neuromodulators on inflammatory markers in a murine microglial cell line.
Hong-Jin Shu, Douglas F Covey, Charles F Zorumski, Steven Mennerick
Abstract read
In one paragraphArticle in The Journal of steroid biochemistry and molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
4 authors.
Hong-Jin ShuDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA.
Douglas F CoveyDepartment of Developmental Biology, Washington University School of Medicine, St Louis, MO 63110, USA; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine, St Louis, MO 63110, USA.
Charles F ZorumskiDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine, St Louis, MO 63110, USA.
Steven MennerickDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine, St Louis, MO 63110, USA. Electronic address: menneris@wustl.edu.
Funding
Neuroactive steroids as novel psychiatric treatments: mechanistic studiesP50MH122379 · NIMH · WASHINGTON UNIVERSITY · PI EVERS, ALEX S. · 2021 to 2025
$12.2MGABAA RECEPTOR POPULATIONS IN HIPPOCAMPUS AND THALAMUSR01MH123748 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2021 to 2025
$2.4MDevelopment of chemical biology tools for NMDA receptorsR01MH110550 · NIMH · WASHINGTON UNIVERSITY · PI COVEY, DOUGLAS F · 2017 to 2021
$2.0MNIMH NIH HHS P50 MH122379NIMH NIH HHS R01 MH110550NIMH NIH HHS R01 MH123748
6 · The paper itselfAbstract
Neuroactive steroids are allosteric modulators of GABA
Indexed as
InflammationMicrogliaNeurosteroidsNeurotransmitter AgentsPregnanoloneSteroidsSterolsAnimalsCell LineCytokinesInterleukin-1betaInterleukin-6LipopolysaccharidesMiceReceptors, GABA-AStructure-Activity RelationshipCytokinesInterleukin-1betaInterleukin-6LipopolysaccharidesNeurosteroidsNeurotransmitter AgentsPregnanoloneReceptors, GABA-ASteroidsSterolsTumor Necrosis Factor-alphaanti-inflammatorycytokinesGABA(A) receptorNeuroactive steroidsoxysterolsstructure-activity
Identifiers
PMID41765147
PMCPMC13175375
What Socratic holds
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