ReviewNaunyn-Schmiedeberg's archives of pharmacology2026
Antimicrobial and antibiofilm actions of iridoids: a comprehensive mechanistic review.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intensive use of antibiotics resulted in the development of resistance, posing a significant global threat to human health. Natural products have garnered significant attention in modern drug discovery and development. Utilizing natural compounds and extracts, either alone or in combination with conventional antimicrobial drugs, could be a significant development in overcoming pathogen resistance mechanisms. Among these natural compounds, iridoids exhibited diverse biological activities, such as anti-inflammatory, antioxidant, anticancer, antidiabetic, antimicrobial, and neuroprotective properties. They are present in some widely available fruits, such as olives, noni, and berries. In this concise review, the utilization of iridoids as a promising approach to combat antimicrobial resistance is discussed. Iridoids exert their antimicrobial effects through various mechanisms including inhibition of microbial growth, disruption and permeability of microbial cell membranes, interference with metabolic pathways, and inhibition of bacterial efflux pumps. Their structural versatilities give them an advantage in targeting a variety of microorganisms.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.