Evidence map›Paper›PMID 41766152›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2026

[A real-world study on the association between treatment of patent ductus arteriosus in extremely preterm infants and the risk of bronchopulmonary dysplasia].

Lyu Wang, Jun-Yan Xi, Jian Gu, Hui-Yuan Tan, Xin-Qi Zhong

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Lyu WangDepartment of Pediatrics, Guangdong Provincial People's Hospital, Guangzhou 510080, China.
Jun-Yan Xi
Jian GuDepartment of Pediatrics, Guangdong Provincial People's Hospital, Guangzhou 510080, China.
Hui-Yuan TanDepartment of Pediatrics, Guangdong Provincial People's Hospital, Guangzhou 510080, China.
Xin-Qi Zhong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine how different ibuprofen treatment regimens affect the occurrence of bronchopulmonary dysplasia (BPD) in extremely preterm infants with patent ductus arteriosus (PDA).

methodsA retrospective case-control study was conducted at the Third Affiliated Hospital of Guangzhou Medical University from September 2017 to December 2019. A total of 230 extremely preterm infants with PDA who met the inclusion criteria were included. The inverse probability of treatment weighting method was applied to evaluate the associations of ibuprofen treatment, the age at treatment initiation, and the total ibuprofen dose in the first course with the risk of BPD.

resultsAmong extremely preterm infants with PDA, the risk of BPD after ibuprofen treatment was 0.326 times that of infants without treatment (

conclusionsIn extremely preterm infants with PDA, ibuprofen treatment and initiating treatment at an age of ≤2 weeks are protective factors for BPD, while use of a high dose in the first course appears to be unrelated to the risk of BPD.

Indexed as

Bronchopulmonary DysplasiaDuctus Arteriosus, PatentIbuprofenCase-Control StudiesFemaleHumansInfant, Extremely PrematureInfant, NewbornMaleRetrospective StudiesIbuprofenBronchopulmonary dysplasiaExtremely preterm infantIbuprofenInverse probability of treatment weightingPatent ductus arteriosus

Identifiers

PMID41766152
PMCPMC12950972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.