Evidence map›Paper›PMID 41766624›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Affinity-Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6-PP-InsP

Kevin Ritter, Verena Gaugler, Sara Christina Stolze, Riya Ghosh, Akhila Jayamon, Ranjana Yadav, Felix Wollensack, Debabrata Laha, Hirofumi Nakagami, Gabriel Schaaf and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kevin RitterFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre For Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, Germany.
Verena GauglerDepartment of Plant Nutritioninstitute of Crop Science and Resource Conservation, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.
Sara Christina StolzeMax Planck Institute for Plant Breeding Research, Protein Mass Spectrometry, Cologne, Germany.
Riya GhoshDepartment of Biochemistry, Division of Biological Sciences, Indian Institute of Science (IISc), Bengaluru, India.
Akhila JayamonDepartment of Biochemistry, Division of Biological Sciences, Indian Institute of Science (IISc), Bengaluru, India.
Ranjana YadavDepartment of Biochemistry, Division of Biological Sciences, Indian Institute of Science (IISc), Bengaluru, India.
Felix WollensackFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre For Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, Germany.
Debabrata LahaDepartment of Biochemistry, Division of Biological Sciences, Indian Institute of Science (IISc), Bengaluru, India.
Hirofumi NakagamiMax Planck Institute for Plant Breeding Research, Protein Mass Spectrometry, Cologne, Germany.
Gabriel SchaafDepartment of Plant Nutritioninstitute of Crop Science and Resource Conservation, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.
Henning Jacob JessenFaculty of Chemistry and Pharmacy, Institute of Organic Chemistry, and CIBSS-Centre For Integrative Biological Signaling Studies, Albert-Ludwigs University Freiburg, Freiburg, Germany.ORCID https://orcid.org/0000-0002-1025-9484

Funding

Deutsche Forschungsgemeinschaft 390732324Deutsche Forschungsgemeinschaft 390939984Deutsche Forschungsgemeinschaft 560443421Deutsche Forschungsgemeinschaft JE 572/11-1Deutsche Forschungsgemeinschaft SCHA1274/5-1Volkswagen Foundation 98604
6 · The paper itself

Abstract

Inositol pyrophosphates (PP-InsPs) are central regulators of eukaryotic signaling events. While certain PP-InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain-containing proteins in plants, the functions of the recently discovered isomer 4/6-PP-InsP

Indexed as

ArabidopsisArabidopsis ProteinsInositol PhosphatesProtein Interaction MappingProtein BindingSignal TransductionArabidopsis ProteinsInositol PhosphatesFHA domainsinositol pyrophosphatesinteractomephotoaffinity pull‐downPP‐InsP

Identifiers

PMID41766624
PMCPMC13159116

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.