ArticleCase reports in oncological medicine2026
Paraneoplastic Pulmonary Embolism Revealing Metastatic Uterine Carcinosarcoma.
Article in Case reports in oncological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Venous thromboembolism (VTE) can be a paraneoplastic phenomenon and may occasionally be the first manifestation of an occult malignancy. We present the case of an elderly woman whose "unprovoked" pulmonary embolism (PE) led to the diagnosis of metastatic uterine carcinosarcoma, an aggressive endometrial cancer subtype. Case: A 74-year-old postmenopausal woman with a history of uterine fibroids and prior breast ductal carcinoma in situ developed progressive dyspnea. She was found to have bilateral PEs with right heart strain and extensive bilateral deep vein thromboses (DVTs). Imaging also revealed ascites, widespread lymphadenopathy, and an 8-cm uterine mass. Tumor marker evaluation showed a markedly elevated CA-125 level. Diagnostic procedures including endometrial biopsy, ascitic fluid cytology, and lymph node biopsy confirmed Stage IVB uterine carcinosarcoma. She was managed with anticoagulation for VTE and initiated on systemic chemotherapy (carboplatin plus paclitaxel), given that surgical cure was not feasible due to metastases. Outcome: After treatment initiation, the patient's respiratory status improved, and she was discharged on long-term anticoagulation and chemotherapy, with plans for outpatient oncology follow-up. Conclusion: This case highlights that an unexplained (unprovoked) PE in an older adult can be the harbinger of an underlying malignancy. In women, especially those with additional red flags such as abdominal distension or abnormal uterine bleeding, prompt evaluation for gynecologic cancers is warranted. Early identification of the occult cancer allowed appropriate therapy; however, uterine carcinosarcoma carries a poor prognosis once metastatic. Clinicians should maintain a high index of suspicion for hidden malignancy in cases of idiopathic VTE, as timely diagnosis can guide life-saving interventions.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.