Evidence map›Paper›PMID 41766769›Full record

ReviewEuropean cardiology2026

Frailty Meets Cardio-oncology: A New Frontier in Personalised Cancer Care.

Ilaria Torre, Lorenzo Tinti, Ludovica Amore, Antonella Lombardo, Massimiliano Camilli

Abstract readReview
In one paragraph

Review in European cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ilaria TorreDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart Rome, Italy.ORCID https://orcid.org/0000-0003-4506-7244
Lorenzo TintiCardiology Division, Ospedale Santa Rosa Viterbo, Italy.
Ludovica AmoreDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart Rome, Italy.
Antonella LombardoDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart Rome, Italy.
Massimiliano CamilliDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart Rome, Italy.ORCID https://orcid.org/0000-0002-2940-5349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, novel cancer therapies have significantly improved patient survival, but they have also introduced clinical challenges, particularly regarding treatment-related cardiovascular toxicity. Frailty is a clinical syndrome characterised by reduced physiological reserve, and is associated with poorer clinical outcomes and an elevated risk of cardiovascular disease. While it is more prevalent among older adults, frailty can also affect cancer patients due to shared pathophysiological mechanisms, such as mitochondrial dysfunction, chronic inflammation and oxidative stress, which may contribute to cancer therapy-induced cardiac damage. However, evidence supporting frailty as a predictive factor for cardiovascular complications in the cardio-oncology setting remains limited. This review emphasises the importance of incorporating frailty assessment into the oncological setting to improve risk stratification and guide personalised therapeutic strategies.

Indexed as

cancerCardio-oncologycardiovascular diseasesfrailtyheart failure

Identifiers

PMID41766769
PMCPMC12937082

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.