Evidence map›Paper›PMID 41767225›Full record

ReviewRSC advances2026

Scaffold-based biomaterials in ovarian tissue engineering.

Chiara Di Berardino, Liliana Liverani, Aldo R Boccaccini, Camila Cecilia Rojo-Fleming, Gianna Sacchetti, Alessia Peserico, Chiara Camerano Spelta Rapini, Giulia Capacchietti, Barbara Barboni

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chiara Di BerardinoDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo 64100 Teramo Italy cdiberardino@unite.it.ORCID https://orcid.org/0000-0002-9202-1858
Liliana LiveraniInstitute of Biomaterials, Department of Materials Science and Engineering, Friedrich-Alexander University of Erlangen-Nuremberg 91054 Erlangen Germany.
Aldo R BoccacciniInstitute of Biomaterials, Department of Materials Science and Engineering, Friedrich-Alexander University of Erlangen-Nuremberg 91054 Erlangen Germany.
Camila Cecilia Rojo-FlemingDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo 64100 Teramo Italy cdiberardino@unite.it.
Gianna SacchettiDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo 64100 Teramo Italy cdiberardino@unite.it.
Alessia PesericoDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo 64100 Teramo Italy cdiberardino@unite.it.ORCID https://orcid.org/0000-0003-2025-2419
Chiara Camerano Spelta RapiniDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo 64100 Teramo Italy cdiberardino@unite.it.
Giulia CapacchiettiDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo 64100 Teramo Italy cdiberardino@unite.it.
Barbara BarboniDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo 64100 Teramo Italy cdiberardino@unite.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid evolution of reproductive tissue engineering has positioned biomaterials as key enabling tools for the development of artificial ovary technologies aimed at fertility preservation and ovarian function restoration. Conventional assisted reproductive technologies mainly target late-stage folliculogenesis and remain inadequate for conditions involving early follicle depletion, such as gonadotoxic cancer therapies and premature ovarian insufficiency. This systematic review, conducted in accordance with PRISMA 2020 guidelines, critically examines biomimetic scaffold strategies for ovarian tissue engineering, focusing on material composition, structural design, biofunctionality and translational relevance. A total of 137 studies were analysed, covering

Identifiers

PMID41767225
PMCPMC12947750

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.