ReviewiScience2026
Anticancer selenopeptides from food sources: synthesis strategies and multitarget mechanisms.
Review in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dual challenges of drug resistance and toxicity in cancer therapy necessitate the development of new drugs with high efficacy and safety. Selenopeptides, which synergistically combine selenium's redox regulation capabilities with the tumor-targeting specificity of peptides, represent a promising frontier in antitumor drug development. Based on the recent literature, this review summarizes the sources and preparation methods of selenium peptides, such as enzymatic hydrolysis and solid/liquid-phase synthesis. Furthermore, it elucidates their multitarget mechanisms of action, including the modulation of the PI3K/Akt signaling pathway, activation of immune cells, inhibition of angiogenesis, and induction of cancer cell apoptosis. Evidence from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.