Evidence map›Paper›PMID 41767378›Full record

ArticleFrontiers in endocrinology2026

Protective role of aqueous

Yuru Xu, Ying Cao, Linen Zou, Wulanna, Xinyu Liu, Shutong Yan, Chengyi Liu, Mengran Gao, Jingke Zhan, Qingchun Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuru Xu *School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ying Cao *School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Linen Zou *School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
WulannaMedical Administration Section, Hohhot Hospital of Mongolian and Chinese Medicine, Hohhot, China.
Xinyu LiuSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Shutong YanSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Chengyi LiuSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Mengran GaoSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jingke ZhanSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Qingchun WangInner Mongolia Academy of Traditional Chinese and Mongolian Medicine, Hohhot, China.
Chongming WuSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To elucidate the protective effects of aqueous Methods: Male mice were fed an HSFD and orally treated with Results: The extract significantly ameliorated HSFD-induced metabolic impairments, including hyperglycemia, hyperlipidemia, insulin resistance, and hepatic steatosis. Histological improvements were observed in the liver, pancreas, and colon. Hepatic expression of FAS, NF-κB, and IL-6 was suppressed, while PPARα and LDLR expression was restored. Antioxidant defenses were enhanced by reducing malondialdehyde and increasing superoxide dismutase activity. Microbiota analysis revealed partial restoration of beneficial taxa such as Conclusion: Aqueous

Indexed as

CoriandrumGastrointestinal MicrobiomeLiverMetabolic DiseasesPlant ExtractsSeedsAnimalsDiet, High-FatMaleMiceOxidative StressPlant ExtractsCoriandrum sativum seedglucose metabolism disordersgut microbiomelipid metabolism disordersoxidative stress

Identifiers

PMID41767378
PMCPMC12946750

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.