Trial reportFrontiers in pediatrics2026
Effects of lung protective ventilation and conventional ventilation on postoperative atelectasis in neonates under general anesthesia.
Trial report in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Background: General anesthesia frequently causes atelectasis, a condition that significantly endangers patient safety during and after surgery, especially in neonates. Evidence suggests that lung protective ventilation (LPV) strategies may reduce the incidence of postoperative atelectasis in patients receiving general anaesthesia; however, the efficacy for neonatal patients remains controversial. This study aims to explore how LPV affects the incidence of atelectasis in neonates. Methods: This randomized controlled trial involved neonatal patients under general anesthesia with mechanical ventilation for over two hours, randomly assigned to receive LPV (including a Vt of 6 mL/kg, 5 cmH Results: The study enrolled 100 neonatal patients, divided into 50 in the LPV group and 50 in the control group. At the conclusion of surgery, the LPV group had a significantly lower incidence of significant atelectasis (18% vs. 58%) and lower median LUS scores [7 [6, 9] vs. 12 [8, 18]] than the control group did (all Conclusions: Compared with conventional ventilation, LPV results in a significantly lower incidence of significant postoperative atelectasis and lower LUS scores in neonates receiving general anaesthesia. Clinical Trial Registration: ClinicalTrials.gov, ChiCTR2100051721.
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