Evidence mapPaperPMID 41767845Full record

ReviewFrontiers in aging neuroscience2026

Gut microbiota and brain aging: a comparative review of African and western populations.

Beulah Favour Ortutu, Abidemi Oluwasanmi Okin, Kwame Osei Darkwah, Uju Maryanne Onuorah, Abdulkadir Yusif Maigoro, Gideon Onyedikachi Iheme

Abstract readReview
In one paragraph

Review in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beulah Favour OrtutuDepartment of Nutrition, Texas A&M University, College Station, TX, United States.
Abidemi Oluwasanmi OkinDepartment of Family and Consumer Sciences, North Carolina Agricultural and Technical State University, Greensboro, NC, United States.
Kwame Osei DarkwahDepartment of Cell and Molecular Biology, School of Science and Engineering, Tulane University, New Orleans, LA, United States.
Uju Maryanne OnuorahDepartment of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Abdulkadir Yusif MaigoroConvergence Research Center for Insect Vectors, Incheon, Republic of Korea.
Gideon Onyedikachi IhemeDepartment of Human Nutrition and Dietetics, Michael Okpara University of Agriculture, Umudike, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the population ages, cognitive decline and neurodegenerative diseases have become major public health concerns. The human gut microbiota plays a major role in regulating neurodevelopment, neuroinflammation, and cognitive decline through the gut-brain axis. Emerging evidence reveals a possible association between alterations in gut microbial diversity and age-related neurological disorders, including Alzheimer's disease and neurodegeneration. Regional and dietary differences shape the gut microbiome. These variations may, in turn, be associated with differences in brain aging across populations. Several cross-sectional studies indicate that rural African communities consuming predominantly fiber-rich diets exhibit distinct gut microbiota profiles characterized by increased abundance of genera, including

Indexed as

Africabrain agingdietgut-brain axisgut microbiotaneurodegenerative disease

Identifiers

PMID41767845
PMCPMC12935954

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.