ReviewFrontiers in bioengineering and biotechnology2026
Integrating platelet-rich plasma therapy into nursing practice: a review of biological mechanisms and clinical applications.
Review in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
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Abstract
Platelet-rich plasma (PRP) therapy, an autologous biologic rich in growth factors, has emerged as a promising modality in regenerative medicine, with expanding relevance in nursing-led care. PRP promotes tissue regeneration, modulates inflammation, and enhances functional recovery in several conditions, including chronic wounds, musculoskeletal disorders, and aesthetic applications. Its minimally invasive nature and patient-specific approach align closely with holistic nursing models. This review synthesizes current evidence on the biological mechanisms underlying PRP activity, including platelet composition, growth factor signaling, and immunomodulation, and critically evaluates clinical outcomes relevant to nursing practice. Particular attention is given to nursing roles throughout the PRP treatment continuum, from patient selection and preparation to monitoring and long-term follow-up. Despite its clinical promise, PRP adoption in nursing practice faces barriers such as formulation variability, lack of standardized protocols, and limited nurse-led guidelines. We propose strategic directions for integrating PRP into evidence-based nursing frameworks, emphasizing digital tools, individualized care pathways, and interdisciplinary collaboration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.