Evidence map›Paper›PMID 41769350›Full record

ArticleFrontiers in cellular and infection microbiology2026

Integrated transcriptomics and molecular docking identify hub genes and statin regulators in

Minglin Zhang, Xue He, Xuelin Zhao, Ting Cai, Xiaoming Liu, Fen Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Minglin Zhang *Health Management Medicine Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xue He *Health Management Medicine Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xuelin ZhaoDepartment of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ting CaiDepartment of Gastroenterology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, China.
Xiaoming LiuDepartment of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Fen WangDepartment of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We identified differentially expressed genes (DEGs) and hub genes, pathway enrichment analysis, transcription factors (TFs), small-molecule drug and molecular docking prediction using gastric epithelial cells (GECs) infected with Results: Conclusion: These findings provide a theoretical foundation for further investigation into the molecular mechanisms underlying

Indexed as

Gastric MucosaHelicobacter InfectionsHelicobacter pyloriHydroxymethylglutaryl-CoA Reductase InhibitorsMolecular Docking SimulationTranscriptomeAnimalsComputational BiologyEpithelial CellsGene Expression ProfilingGene Regulatory NetworksHumansSignal TransductionTranscription FactorsHydroxymethylglutaryl-CoA Reductase InhibitorsTranscription FactorsatorvastatinHelicobacter pylorihub genesmolecular dockingsimvastatinTPCA-1

Identifiers

PMID41769350
PMCPMC12945777

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.