Evidence mapPaperPMID 41769631Full record

ReviewCureus2026

A Bibliometric Analysis Review of the Top 50 Most Cited Articles on Incretin-Based Therapy for Weight Reduction and Diabetes Management.

Ehab F Alsaygh, Abdullah M Aljarboa, Adel A Alhazmi, Abdullah S Alhazmi, Osamah A Alraddadi, Aseel A Althagafi, Mohmmed F Alhojele

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ehab F AlsayghFamily Medicine, Family Medicine Academy, Ministry of Health, Medina, SAU.
Abdullah M AljarboaFamily Medicine, Family Medicine Academy, Ministry of Health, Medina, SAU.
Adel A AlhazmiFamily Medicine, Ministry of National Guard Health Affairs, Jeddah, SAU.
Abdullah S AlhazmiFamily Medicine, Family Medicine Academy, Ministry of Health, Medina, SAU.
Osamah A AlraddadiFamily Medicine, Ministry of National Guard Health Affairs, Jeddah, SAU.
Aseel A AlthagafiFamily Medicine, Ministry of National Guard Health Affairs, Jeddah, SAU.
Mohmmed F AlhojeleObesity and Family Medicine, King Salman Bin Abdulaziz Medical City, Medina, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The introduction of incretin-based therapy has brought a significant transformation in the treatment of type 2 diabetes and obesity. It works by augmenting natural incretin hormones to enhance insulin secretion and suppress glucagon release in a glucose-dependent manner. The primary goal of this research was to identify the top 50 most cited articles in this field, explore the trends, recent developments and the future direction of the research in this field. This is a bibliometric analysis. The subjects consisted of the 50 most cited scientific publications that were extracted from the Web of Science Core Collection on May 11, 2025. The research strategy used keywords related to incretin therapy, weight loss and type-2 diabetes. The research approach consisted of a database search combined with a quantitative assessment of publication metrics. The articles we identified were published between 1999 and 2023. Statistical analysis used IBM SPSS Statistics for Windows, Version 31 (Released 2025; IBM Corp., Armonk, New York, United States) to calculate descriptive statistics including mean, standard deviation, median and frequencies for data summary. The 50 articles received an average of 473.44 citations with a citation range between 188 and 3,045. The majority of publications appeared in Q1 journals with impact factors ranging from 2.2 to 98.4 and Diabetes Care (28%) and The Lancet (14%) being the most prominent journals. Thirteen countries contributed, predominantly the United States (56%), followed by Denmark (10%). The analysis successfully identified the most influential literature, confirming the significant and growing impact of incretin-based therapy research. The field demonstrates a clear trend from GLP-1 agonists towards dual and triple receptor agonists, with research heavily published in high-impact journals and led by US-based, multi-author teams.

Indexed as

bibliometricdiabetesdpp-4 inhibitorsglp-1 receptor agonistsincretinliraglutideobesitysemaglutideweight loss

Identifiers

PMID41769631
PMCPMC12948323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.