Evidence map›Paper›PMID 41770414›Full record

ReviewJournal of physiology and biochemistry2026

Research progress of ferroptosis in obesity and its complications.

Jiamei Zhang, Mengmeng Tang, Min Yu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of physiology and biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiamei ZhangDepartment of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Mengmeng TangDepartment of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Min YuDepartment of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. myu@njmu.edu.cn.ORCID http://orcid.org/0009-0009-6506-5685

Funding

National Natural Science Foundation of China 82001141Natural Science Foundation of Jiangsu Province BK20201084
6 · The paper itself

Abstract

Obesity is a global issue and has emerged as a significant public health challenge worldwide. It is defined by excess fat accumulation in the body, leading to various metabolic issues. Ferroptosis, an iron-dependent form of regulatory cell death (RCD), is marked by intracellular iron overload and lipid peroxide accumulation. Numerous researches have shown that ferroptosis is closely associated with the development and progression of various diseases. Dysregulation of lipid metabolism and deposition due to iron overload play a crucial role in obesity, creating conditions conducive to ferroptosis. Consequently, ferroptosis may become a key target for pharmacological treatment of obesity. In this paper, we provide an overview of the mechanisms of ferroptosis occurrence and regulation, and discuss the research progress of ferroptosis in obesity, which will provide a new direction for the prevention and treatment of obesity and other metabolic diseases in the future.

Indexed as

FerroptosisIron OverloadObesityAnimalsHumansIronLipid MetabolismIronFerroptosisIron metabolismLipid metabolismObesityReview

Identifiers

PMID41770414

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.