ReviewInvestigative and clinical urology2026
Mechanisms and clinical implications of bacterial persistence in recurrent urinary tract infections.
Review in Investigative and clinical urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Proactive Cystoscopic Debris Removal for Reducing Catheter Blockage in Patients with Long-Term Indwelling Catheters: A Prospective Self-Selected Cohort Study with Exploratory Subgroup Analysis on Urinary Tract Infections.Journal of clinical medicine · 2026Article
- Double agent: how Escherichia coli switches from commensal to pathogen in the urinary tract infection.Infection · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recurrent urinary tract infections (rUTIs) represent a significant clinical challenge, particularly among women and catheterized patients, leading to diminished quality of life and increased healthcare utilization. A central factor in rUTI pathogenesis is bacterial persistence despite seemingly appropriate antibiotic therapy. Unlike classical antibiotic resistance, persistence involves phenotypic adaptations that allow uropathogens to evade both host immune responses and antimicrobial agents. This review examines the multifactorial mechanisms underlying bacterial persistence, including intracellular survival strategies, biofilm formation, antibiotic tolerance, and host immune evasion. An improved understanding of these processes is essential for developing novel, targeted therapeutic strategies that go beyond traditional antimicrobial approaches and address the root causes of recurrence.
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