Evidence map›Paper›PMID 41775632›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2026

RGR-Mediated Photopic Visual Cycle and Oxidative Stress: Potential Mechanisms for Cone Vision Impairment and Retinal Degeneration in Retinitis Pigmentosa Linked to D1080N-IRBP.

Songhua Li, Kota Sato, Minghao Jin

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Songhua LiNeuroscience Center of Excellence, LSU Health New Orleans School of Medicine, New Orleans, Louisiana 70112.
Kota SatoNeuroscience Center of Excellence, LSU Health New Orleans School of Medicine, New Orleans, Louisiana 70112.ORCID 0000-0002-0176-5545
Minghao JinNeuroscience Center of Excellence, LSU Health New Orleans School of Medicine, New Orleans, Louisiana 70112.ORCID 0000-0002-6790-8860

Funding

IRBP in the visual cycles and retinal diseasesR01EY036015 · NEI · LSU HEALTH SCIENCES CENTER · PI Minghao Jin · 2024 to 2026
$1.1M
RPE apical proteins that regulate the visual cycleR21EY028255 · NEI · LSU HEALTH SCIENCES CENTER · PI JIN, MINGHAO · 2020 to 2021
$399k
NEI NIH HHS R01 EY036015NEI NIH HHS R21 EY028255
6 · The paper itself

Abstract

Interphotoreceptor retinoid-binding protein (IRBP), an extracellular glycoprotein, supports cone-mediated vision through unclear molecular mechanisms. Over 30 different mutations in the

Indexed as

Color VisionEye ProteinsOxidative StressRetinal Cone Photoreceptor CellsRetinal DegenerationRetinitis PigmentosaRetinol-Binding ProteinsAnimalsFemaleHumansMaleMiceMice, Inbred C57BLMice, TransgenicMutationReceptors, G-Protein-CoupledEye ProteinsG protein-coupled receptor RGRReceptors, G-Protein-CoupledRetinol-Binding ProteinsRetinol-Binding Proteins, Interstitialcone photoreceptorIRBPretinal dystrophyRGRvisual cycle

Identifiers

PMID41775632
PMCPMC13064807

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.