ArticleCommunications medicine2026
Increased physical performance after personalised physiotherapy and nutritional counselling in adults with post-COVID-19 condition: a feasibility randomised trial.
Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05254301 (Faster Functional Performance Recovery After Individualized Nutrition Therapy Combined With a Patient-tailored Physical Rehabilitation Program Versus Standard Physiotherapy in Patients With Long COVID), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Faster Functional Performance Recovery After Individualized Nutrition Therapy Combined With a Patient-tailored Physical Rehabilitation Program Versus Standard Physiotherapy in Patients With Long COVID: a Pilot Study.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNutritional counselling and physiotherapy could provide synergistic effects in alleviating Post-COVID-19 Condition (PCC) symptoms. However, the feasibility of such personalised multimodal therapy (PMT) remains unclear. The aim was to examine feasibility and inform a future randomised controlled trial (RCT) by exploring preliminary clinical outcomes.
methodsThis pilot and feasibility parallel-group RCT was conducted at a tertiary hospital (ClinicalTrials.gov: NCT05254301, KCE-trials funding: LCOV-211306). Adult participants with PCC according to the WHO criteria were block-randomised into either physiotherapy (n = 33) or PMT (n = 32) for 12 weeks with 6-week follow-up. The PMT included online nutritional counselling and pacing-based physiotherapy. Outcome assessment was assessor-blinded. Feasibility outcomes included study burden, recruitment, and attrition. The 1-min sit-to-stand test (1-MSTS) was assessed as an exploratory clinical outcome. Descriptive statistics and 95% confidence intervals (95% CI) were used to estimate between-group differences. Analyses used all available data, with varying sample sizes.
resultsHere we show that study burden was higher than expected, affecting both recruitment and attrition. The PMT group attended 10 ± 4 dietitian teleconsultations and 14 ± 4 supervised physiotherapy sessions. Between-group mean differences in 1-MSTS repetitions from baseline were 0.97 [95% CI: -1.75, 3.70] at 12 weeks and 2.14 [95% CI: -1.26, 5.54] at follow-up. A definitive RCT would require 41 participants.
conclusionsThe study demonstrated overall safety and feasibility despite a high study burden. Exploratory clinical outcomes showed potential improvement in both groups, with growing estimated differences between groups over time, suggesting a longer follow-up for a definitive RCT.
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Registered trials
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