Evidence map›Paper›PMID 41775937›Full record

ReviewNPJ cardiovascular health2025

Role of biomechanical factors in plaque rupture and erosion: insight from intravascular imaging based computational modeling.

Liang Wang, Yanwen Zhu, Chen Zhao, Akiko Maehara, Rui Lv, Xiaoya Guo, Mingming Yang, Gary S Mintz, Dalin Tang, Haibo Jia and 1 more

Erratum issuedAbstract readReview
In one paragraph

Review in NPJ cardiovascular health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Liang WangSchool of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Yanwen ZhuSchool of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Chen ZhaoState Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Department of Cardiology of the Second Affiliated Hospital, Harbin Medical University, Harbin, 150086, China.
Akiko MaeharaCardiovascular Research Foundation, Columbia University, New York, NY, 10022, USA.
Rui LvDepartment of Cardiovascular Surgery, Shandong Second Provincial General Hospital, Jinan, 250022, China.
Xiaoya GuoSchool of Science, Nanjing University of Posts and Telecommunications, Nanjing, 210023, China.
Mingming YangDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Gary S MintzCardiovascular Research Foundation, Columbia University, New York, NY, 10022, USA.
Dalin TangSchool of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China. dtang@wpi.edu.
Haibo JiaState Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Department of Cardiology of the Second Affiliated Hospital, Harbin Medical University, Harbin, 150086, China. jhb101180@163.com.
Bo YuState Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Department of Cardiology of the Second Affiliated Hospital, Harbin Medical University, Harbin, 150086, China.

Funding

Basic Research Plan Natural Science Foundation of Jiangsu Province BK20232023Key R&D project of Heilongjiang Province 2022ZX06C07National Natural Science Foundation of China 11802060National Natural Science Foundation of China 11972117National Natural Science Foundation of China 81722025Natural Science Foundation of Shandong Province ZR2024QA110
6 · The paper itself

Abstract

Coronary biomechanics including structural wall stress and strain on the vessel wall and flow wall shear stress on the endothelial surface play a vital role in plaque progression, rupture and erosion. This review summarizes recent advances in coronary intravascular imaging, image-based biomechanical modeling, and their applications in investigating possible biomechanical mechanisms of plaque rupture and erosion, and developing interventional therapies targeting unfavorable mechanical conditions for personalized treatment and precision medicine.

Identifiers

PMID41775937
PMCPMC12912356

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.