Evidence map›Paper›PMID 41775946›Full record

SynthesisThe international journal of cardiovascular imaging2026

Prognostic impact of myocardial bridge on long-term mortality and morbidity: A meta-analysis and systematic review.

Yasir Salah Alam, Hussein Nafakhi, Liwaa Mahdi, Alaa Salah Jumaah, Mohammed Saeed Abdulzahra, Hassan Abdulla Al-Aquli, Akeel Abed Yasseen

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in The international journal of cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yasir Salah AlamDepartment of Internal medicine, Faculty of Medicine, University of Kufa, P.O. Box 21, Kufa, Iraq.ORCID http://orcid.org/0000-0001-7913-3727
Hussein NafakhiDepartment of Internal medicine, Faculty of Medicine, University of Kufa, P.O. Box 21, Kufa, Iraq. husseinaf.alnaffakh@uokufa.edu.iq.ORCID http://orcid.org/0000-0002-0238-0460
Liwaa MahdiDepartment of Pathology and Forensic Medicine, Faculty of Medicine, University of Kufa, P.O. Box 21, Kufa, Iraq.ORCID http://orcid.org/0000-0002-2310-2419
Alaa Salah JumaahDepartment of Pathology and Forensic Medicine, Faculty of Medicine, University of Kufa, P.O. Box 21, Kufa, Iraq.ORCID http://orcid.org/0000-0001-9709-1460
Mohammed Saeed AbdulzahraDepartment of Internal medicine, Faculty of Medicine, University of Kufa, P.O. Box 21, Kufa, Iraq.ORCID http://orcid.org/0000-0002-9377-7876
Hassan Abdulla Al-AquliDepartment of general surgery, Faculty of Medicine, University of Kufa, P.O. Box 21, Kufa, Iraq.ORCID http://orcid.org/0009-0009-2193-2388
Akeel Abed YasseenDepartment of Pathology and Forensic Medicine, Faculty of Medicine, University of Kufa, P.O. Box 21, Kufa, Iraq.ORCID http://orcid.org/0000-0001-5050-4408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical relevance of myocardial bridge (MB) remains uncertain and inconsistently reported across studies. This study aimed to assess the relationship between MB and long-term mortality and morbidity, while accounting for the influence of varying patient populations and diagnostic methods used to detect MB.

methodsA comprehensive literature search was conducted to identify studies published up to December 2024 that examined the association between MB and adverse outcomes, including all-cause death (ACD), cardiovascular death (CVD), and major adverse cardiac events (MACE).

resultsA total of 22 studies involving 37,940 participants were included in the analysis. MB was not significantly associated with an increased risk of ACD or CVD. However, MB showed a significant association with MACE, with a pooled hazard ratio (HR) of 1.958 (95% CI: 1.490-2.572; P < 0.001) across 19 studies. Subgroup analysis indicated that MB identified through conventional coronary angiography was significantly linked to a higher risk of MACE (pooled HR: 1.992; 95% CI: 1.432-2.772; P < 0.001), whereas MB detected using multi-detector computed tomography did not show a statistically significant association with MACE. Among high-risk groups, such as patients with hypertrophic cardiomyopathy and those with high-risk coronary artery disease, MB was associated with a notably increased risk of MACE, with pooled HRs of 2.174 (95% CI: 1.067-4.426; P = 0.032) and 3.435 (95% CI: 1.732-6.810; P < 0.001), respectively.

conclusionsMB was associated with an increased relative risk of MACE in pooled analyses but showed no significant association with isolated ACD or CVD.

Indexed as

Myocardial BridgingAdultAgedAged, 80 and overCause of DeathCoronary AngiographyFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsTime FactorsMeta-analysisMorbidityMortalityMyocardial bridge

Identifiers

PMID41775946

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.