Evidence map›Paper›PMID 41775962›Full record

ReviewNPJ cardiovascular health2025

Methods to model epicardial adipose tissue-mediated atrial fibrillation.

L C Cook, M D Perry, A P Hill, J Thorpe

Abstract readReview
In one paragraph

Review in NPJ cardiovascular health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Abnormal "Frontiers in cardiovascular medicine · 2026
    Trial
  2. Article
  3. Review
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

L C CookVictor Chang Cardiac Research Institute, Darlinghurst, Australia.
M D PerryVictor Chang Cardiac Research Institute, Darlinghurst, Australia.
A P HillVictor Chang Cardiac Research Institute, Darlinghurst, Australia.
J ThorpeVictor Chang Cardiac Research Institute, Darlinghurst, Australia. J.Thorpe@victorchang.edu.au.

Funding

Medical Research Future Fund 2024443
6 · The paper itself

Abstract

Obesity is a major risk factor for atrial fibrillation (AF), partly mediated through an increased volume of epicardial adipose tissue (EAT) which directly interacts with the adjacent myocardium. However, the specific underlying mechanisms remain unclear. This narrative review explores animal models, human tissues and in vitro studies used to investigate EAT-mediated AF which can contribute to our understanding of cellular and molecular interactions and potentially elucidate new therapeutic targets.

Identifiers

PMID41775962
PMCPMC12912358

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.