Evidence map›Paper›PMID 41776245›Full record

ArticleNpj biological timing and sleep2025

Comprehensive integrative analysis of circadian rhythms in human saliva.

Nina Nelson, Deeksha Malhan, Janina Hesse, Ouda Aboumanify, Müge Yalçin, Georg Lüers, Angela Relógio

Abstract read
In one paragraph

Article in Npj biological timing and sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nina NelsonInstitute for Systems Medicine and Faculty of Human Medicine, MSH Medical School Hamburg, Hamburg, Germany.
Deeksha MalhanInstitute for Systems Medicine and Faculty of Human Medicine, MSH Medical School Hamburg, Hamburg, Germany.
Janina HesseInstitute for Systems Medicine and Faculty of Human Medicine, MSH Medical School Hamburg, Hamburg, Germany.
Ouda AboumanifyMolecular Cancer Research Center (MKFZ), Medical Department of Haematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Müge YalçinInstitute for Systems Medicine and Faculty of Human Medicine, MSH Medical School Hamburg, Hamburg, Germany.
Georg LüersFaculty of Human Medicine, MSH Medical School Hamburg, Hamburg, Germany.
Angela RelógioInstitute for Systems Medicine and Faculty of Human Medicine, MSH Medical School Hamburg, Hamburg, Germany. angela.relogio@medicalschool-hamburg.de.

Funding

Rolf M. Schwiete Stiftung 07/2019
6 · The paper itself

Abstract

The circadian clock orchestrates vital physiological functions, with its dysregulation implicated in various pathologies. Assessing human clock status via the measurement of circadian rhythms is crucial for health management and disease treatment. Saliva provides a non-invasive means for such analysis. In this study, we examined circadian rhythms and related parameters in 21 healthy individuals (n = 4 - 19 per experiment), assessing different data types, including saliva gene expression with our TimeTeller

Identifiers

PMID41776245
PMCPMC12912387

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.