Evidence mapPaperPMID 41776749Full record

ArticleEndocrinology, diabetes & metabolism2026

Bridging Minds and Behaviours: Patient Empowerment Mediates Psychological Factors and Diabetes Self-Management.

Shujie Liu, Fei Chen, Fangli Tang, Wenjun Wang, Xiaodan Yuan, Dan Cheng, Yetong Wang, Qingqing Lou

Abstract readMulticenter Study
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Shujie LiuHainan Clinical Research Center for Metabolic Disease, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Fei ChenCollege of Nursing, Henan University of Science and Technology, Luoyang, Henan, China.
Fangli TangDepartment of Endocrinology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Wenjun WangHainan Clinical Research Center for Metabolic Disease, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Xiaodan YuanDepartment of Public Health, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jangsu, China.
Dan ChengDepartment of Hematology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Yetong WangDepartment of Renal Department and Hemodialysis, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, Henan, China.
Qingqing LouDepartment of Endocrinology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.ORCID https://orcid.org/0000-0002-4743-0900

Funding

National Natural Science Foundation of China 12561049National Natural Science Foundation of China 72164010
6 · The paper itself

Abstract

objectivesThis multicenter cross-sectional study was designed to verify whether patient empowerment mediates the relationship between psychosocial factors and diabetes self-management behaviours and HbA1c. Patient empowerment is a key factor improving diabetes management. The mechanism underneath is less clear.

methodsWe conducted a multicenter cross-sectional study of 2005 type 2 diabetes from five university hospitals across diverse Chinese regions between December 2022 and May 2023. Demographic and lab values came from electronic medical record systems (EMS) while psychological factors were assessed via self-administered digital scales on a WeChat mini-program. The study examined patient empowerment's mediating role between psychological factors (Type D personality, DD, attitudes, subjective norms, perceived control, behaviour change intentions) and diabetes outcomes using mediation and chain mediation analyses.

resultsPatients with lower empowerment scores had shorter disease duration, poorer glycemic control, a higher prevalence of dyslipidemia and multiple complications, and greater socioeconomic disadvantage. Type D personality (OR = 2.201, p < 0.001) and diabetes distress (DD, OR = 1.053, p < 0.001) were identified as independent risk factors for low empowerment. Moreover, patient empowerment significantly mediated the associations between psychosocial factors and both self-management behaviours and HbA1c. Mediation analyses showed significant indirect effects of Type D personality (γ = -0.794, p < 0.001), DD (γ = -0.050, p = 0.024), attitude toward behaviour change (γ = 0.470, p < 0.001), subjective norm (γ = 0.287, p < 0.001), perceived behavioural control (γ = 0.489, p < 0.001) and behavioural intention (γ = 0.458, p < 0.001) on self-management behaviours through empowerment.

conclusionPatient empowerment functions as a critical mediator linking psychosocial factors to self-management behaviours and glycemic control in individuals with type 2 diabetes. Type D personality and DD represent important risk factors for low empowerment. These findings suggest that patient empowerment-focused interventions may enhance diabetes self-management and glycemic control.

Indexed as

Diabetes Mellitus, Type 2EmpowermentPatient ParticipationSelf-ManagementAgedChinaCross-Sectional StudiesFemaleGlycated HemoglobinGlycemic ControlHealth BehaviorHumansMaleMiddle AgedType D PersonalityGlycated Hemoglobinhemoglobin A1c protein, humandiabetes distressempowermentself‐management behaviourstheory of planned behaviourType D personality

Identifiers

PMID41776749
PMCPMC12956832

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.