ArticleJournal of geriatric cardiology : JGC2026
Evaluating the association between oral microbiota and cardiovascular diseases: evidence from Mendelian randomization analysis.
Article in Journal of geriatric cardiology : JGC, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Methodological considerations in Mendelian randomization analyses of oral microbiota and cardiovascular disease.Journal of geriatric cardiology : JGC · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Recent studies have suggested a potential role of the oral microbiome in the development of cardiovascular diseases. This study aims to investigate the association between oral microbiota and cardiovascular disease risk, including atrial fibrillation, myocardial infarction, chronic heart failure, and hypertension. Methods: We analyzed GWAS data from East Asian populations' oral microbiome, involving 2,017 tongue and 1,915 saliva samples from 2,984 individuals with whole-genome sequencing. Additionally, we sourced cardiovascular disease GWAS data from NBDC, including atrial fibrillation (8,180 cases, 28,621 controls), myocardial infarction (14,992 cases, 146,214 controls), chronic heart failure (10,540 cases, 168,186 controls), and systolic blood pressure (145,505 individuals). Results: Several oral microbiota taxa were found to be significantly associated with cardiovascular disease outcomes. Specific microbiota, such as Conclusion: Our findings suggest that the oral microbiota may influence the development and progression of cardiovascular diseases, providing new insights into the potential impact of oral health on cardiovascular risk.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.