Efficacy analysis of quadruple nerve decompression surgery for lower limb diabetic peripheral neuropathy.

Objective: To explore the efficacy of quadruple nerve decompression in treating painful diabetic peripheral neuropathy (PDPN) of lower extremity, and to evaluate its clinical value in pain relief and sensory recovery. Method: A retrospective analysis was performed on 26 PDPN patients (45 sides), all of whom underwent quadruple nerve decompression, including release of the common peroneal nerve (CPN), superficial peroneal nerve (SPN), deep peroneal nerve (DPN), and tibial nerve (TN). Changes in the Visual Analog Scale (VAS) score, two-point discrimination (TPD), sensory nerve conduction velocity (SCV), and Toronto Clinical Scoring System (TCSS) score were evaluated by comparing preoperative values with those at an average of 30.46 months postoperatively. Statistical analysis was conducted using the paired Results: Postoperative VAS scores were significantly reduced, from 7.31 ± 1.62 to 2.51 ± 1.47 ( Conclusion: Significant pain relief and improvement in sensation and nerve function have been achieved in patients with PDPN through quadruple nerve decompression, which addresses multiple potential nerve entrapment sites. This procedure, building upon existing evidence, demonstrates sustained efficacy in pain relief and sensory recovery over a median 30-month follow-up, offering a refined surgical option for patients with refractory PDPN who have failed conservative management.