Evidence mapPaperPMID 41777809Full record

ArticleAcademia medicine and health2026

Clinical burden of dry eye disease in patients with ocular graft versus host disease.

Cherie B Nau, Muriel M Schornack, Jennifer S Harthan, Jennifer S Fogt, Amy C Nau, William J Hogan, Ellen S Shorter

Abstract read
In one paragraph

Article in Academia medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cherie B NauDepartment of Ophthalmology, Mayo Clinic, Rochester, MN, USA.
Muriel M SchornackDepartment of Ophthalmology, Mayo Clinic, Rochester, MN, USA.
Jennifer S HarthanIllinois College of Optometry, Chicago, IL, USA.
Jennifer S FogtCollege of Optometry, The Ohio State University, Columbus, OH, USA.
Amy C NauForefront Eye Care, Boston, MA, USA.
William J HoganDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Ellen S ShorterDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.

Funding

NCATS NIH HHS UL1 TR002003
6 · The paper itself

Abstract

Background: Ocular graft-versus-host disease (oGVHD) is a frequent complication after hematopoietic stem cell transplant, with dry eye being the most common presentation. Patient experience with dry eye from oGVHD may negatively affect quality of life. The purpose of this study was to evaluate patients' perspectives on the symptoms, treatments, and care burdens associated with dry eye from oGVHD. Materials and methods: An electronic questionnaire was sent to patients with dry eye asking about their diagnoses, symptoms, treatments, and experiences associated with dry eye. Results: Of the 639 patients who responded to the questionnaire, 79 reported having dry eye from oGVHD and were included in the analysis. The mean (SD) age of these patients was 55 (10) years (range, 22-73 years; Conclusions: Dry eye symptoms and treatments, along with the associated time and financial costs required, are a burden to patients with oGVHD. These patients should be evaluated by a knowledgeable eye care professional to best treat and manage their disease.

Indexed as

dry eye diseasemeibomian gland dysfunctionocular graft-versus-host diseasescleral contact lensstem cell transplant

Identifiers

PMID41777809
PMCPMC12951619

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.