ArticleFrontiers in endocrinology2026
Risk and all-cause mortality of high low-density lipoprotein cholesterol-albumin ratio level in stable coronary artery disease patients following percutaneous coronary intervention.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Both low-density lipoprotein cholesterol (LDL-C) and albumin are well-established predictors of adverse outcomes in patients with stable coronary artery disease (CAD) who have undergone percutaneous coronary intervention (PCI). However, the risk and all-cause mortality (ACM) of the LDL-C-albumin ratio (LAR)-a composite index integrating these two parameters-remains unclear. Methods: This study enrolled 198 consecutive patients with newly diagnosed stable CAD who underwent PCI at Shinonoi General Hospital between 2014 and 2017. The primary aim was to assess the risks related to high LAR levels and the association between LAR and ACM in this population. Results: The association between the LAR and ACM was evaluated through multiple methods. Analyzed as a continuous variable, each 1 mg/g increase in LAR conferred a 6% higher adjusted risk of ACM (Hazard Ratio [HR] 1.06, 95% Confidence Interval [95% CI] 1.00-1.12, Conclusions: High level LAR is associated with ACM in stable CAD patients following PCI, with a level above 32.5 mg/g distinguishing a high-risk subgroup that warrants closer clinical monitoring due to a significantly elevated risk of adverse outcomes.
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