Trial reportPain management2026
Verbal framing, rather than measured cognitive-affective variables, is associated with short-term outcomes after spinal manipulation: a secondary analysis of a randomized controlled trial.
Trial report in Pain management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06537739 (Influence of Verbal Suggestion on the Therapeutic Effect of the Joint Manipulation of the Lumbar Spine in Patients with Chronic Non-specific Low Back Pain), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Verbal Suggestion on the Therapeutic Effect of the Joint Manipulation of the Lumbar Spine in Patients with Chronic Non-specific Low Back Pain
Who cites it
1 citing paper in PubMed.
- Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications.Experimental physiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPre-treatment communication may influence short-term responses to spinal manipulation. This secondary analysis examined associations between expectations, attitude toward manual therapy, expectation fulfillment, and pain intensity (NPRS-11) and lumbar pressure pain threshold (PPT) across verbal framings.
methodsSixty-six young adults with chronic nonspecific low back pain were randomized to positive, neutral, or negative verbal framing delivered before lumbar spinal manipulation. NPRS-11 and lumbar PPT (L3-L5) were assessed at baseline (t0), immediately post-intervention (t1), and 24 hours post-intervention (t2). Group-specific correlation analyses and multiple linear regression were performed.
resultsAssociations were sparse and inconsistent. Expectation fulfillment assessed at t2 showed no consistent associations with NPRS-11 or PPT at t1 or t2. In the positive group, higher expectations correlated with higher immediate PPT at t1 L4 (
conclusionsShort-term NPRS-11 and lumbar PPT were associated with verbal framing rather than with cognitive-affective variables. CLINICAL
trial registrationThe ClinicalTrial.gov identifier is NCT06537739.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.