Evidence mapPaperPMID 41778788Full record

ArticleMicrobiology spectrum2026

Gut microbial community structure, metabolic signature, and resistome in dyslipidemia: implications for cardiovascular disease management.

Soomin Lee, Hyung-Lae Kim, Shahbaz Raza, Eun-Ju Lee, Yoosoo Chang, Seungho Ryu, Juhee Cho, Han-Na Kim

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Soomin Lee *Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, , Seoul, Republic of Korea.
Hyung-Lae Kim *Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.
Shahbaz RazaDepartment of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, , Seoul, Republic of Korea.
Eun-Ju LeeDepartment of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, , Seoul, Republic of Korea.
Yoosoo ChangDepartment of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, , Seoul, Republic of Korea.
Seungho RyuDepartment of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, , Seoul, Republic of Korea.ORCID 0000-0002-3927-8646
Juhee ChoDepartment of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, , Seoul, Republic of Korea.
Han-Na KimDepartment of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, , Seoul, Republic of Korea.ORCID 0000-0001-7053-7469

Funding

National Research Foundation of Korea RS-2023-NR077149
6 · The paper itself

Abstract

Dyslipidemia, characterized by abnormal blood lipid levels, constitutes a significant risk factor for cardiovascular disease. Emerging evidence indicates that the gut microbiota influences lipid metabolism, although findings across studies have been inconsistent. In this cross-sectional investigation, we analyzed the composition of gut microbiota, associated metabolic pathways, predicted gut metabolites, and the resistome in 1,384 participants (including 895 individuals with dyslipidemia and 489 controls) through shotgun metagenomic sequencing. Our findings demonstrated that

Indexed as

BacteriaCardiovascular DiseasesDyslipidemiasGastrointestinal MicrobiomeCross-Sectional StudiesFemaleHumansLipid MetabolismMaleMetagenomicsMiddle Agedcardiovascular diseasedyslipidemiafunctional profilinggut microbiomeshotgun metagenomics

Identifiers

PMID41778788
PMCPMC13055376

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.