Eco-Conscious Synthesis and Biomedical Profiling of Monometallic and Bimetallic Nanosystems for Targeted Drug Delivery.

Amina Hussain, Imran Haider, Rashed M Almuqbil, Hossam S El-Beltagi

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Article in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Amina HussainFatima Jinnah Women University, The Mall, Punjab, Rawalpindi, 46000, Pakistan. amina.hussain878@gmail.com.

Imran HaiderNational Research Center of Intercropping, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan. imran.haider@iub.edu.pk.ORCID http://orcid.org/0009-0003-1967-4099

Rashed M AlmuqbilDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.

Hossam S El-BeltagiAgricultural Biotechnology Department, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa, 31982, Saudi Arabia. helbeltagi@kfu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents the green biosynthesis, characterization and biomedical assessment of monometallic (gold, selenium and silver) and bimetallic (silver-selenium and silver-gold) green nano system with their drug conjugates using lychee seed extracts. UV-visible spectroscopy confirmed the nanostructure formation, with plasmon resonance peaks specific to each nanostructure. The spherical shape and crystalline character of the nanostructure, which ranged from 10 to 90 nm on average, were verified by transmission electron microscopy (TEM) and X-ray diffraction (XRD) studies. Energy-dispersive X-ray spectroscopy (EDS) analysis was used to verify the elemental composition. Among the synthesized nanoparticles, silver-selenium and silver-gold were selected for drug loading with 5-Fluorouracil, showing efficient encapsulation (55.07 ± 0.07% and 36.23 ± 0.09%, respectively) and sustained morphological integrity after drug incorporation. The IC

Indexed as

Drug Delivery SystemsFluorouracilGoldGreen Chemistry TechnologyMetal NanoparticlesSilverAnimalsAntioxidantsHumansSeleniumAntioxidantsFluorouracilGoldSeleniumSilver5-FluorouracilAntioxidant activityBimetallic nanoparticlesBiocompatibilityDrug deliveryGreen synthesis

Identifiers

PMID41779332

DOI10.1007/s12010-026-05604-1

What Socratic holds

Textmetadata

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.