Evidence map›Paper›PMID 41779859›Full record

ArticleScience advances2026

Differential

Christen M Crosta, Brandon J Vaglio, Joshua Stuckey, Atul K Bhattiprolu, Johanne Solis, Jared Lamp, Andrew Umstead, Irving E Vega, Steven M Silverstein, Bonnie L Firestein

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christen M CrostaDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.ORCID 0000-0003-1975-2782
Brandon J VaglioDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.ORCID 0000-0002-2016-9212
Joshua StuckeyDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.ORCID 0000-0002-9695-2211
Atul K BhattiproluDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.ORCID 0000-0003-2939-4309
Johanne SolisBrain Health Institute, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.ORCID 0009-0007-2113-1746
Jared LampIntegrated Mass Spectrometry Unit, Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA.ORCID 0000-0002-7187-7657
Andrew UmsteadIntegrated Mass Spectrometry Unit, Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA.
Irving E VegaIntegrated Mass Spectrometry Unit, Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA.ORCID 0000-0002-7960-9534
Steven M SilversteinDepartment of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-0699-0960
Bonnie L FiresteinDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.ORCID 0000-0002-1679-3565

Funding

Metabolic Mechanisms of Recovery in Mild TBIR01NS135406 · NINDS · UNIVERSITY OF KENTUCKY · PI BONNIE L FIRESTEIN, DAVID F MEANEY · 2024 to 2026
$1.8M
NINDS NIH HHS R01 NS135406
6 · The paper itself

Abstract

Schizophrenia (SCZ) is heterogenous and polygenic, making it difficult to diagnose and treat. This is expected as diagnostic criteria are solely based on behavioral markers. There is a critical need for easy-to-collect biomarkers that aid in treatment. To identify potential biomarkers, we recruited patients with SCZ and controls. Using buccal cell lysates, we performed real-time quantitative polymerase chain reaction and identified significant differences in

Indexed as

Chaperonin 60Mouth MucosaSchizophreniaAdultBiomarkersCase-Control StudiesFemaleGene Expression RegulationHumansMaleMiddle AgedRNA, MessengerBiomarkersChaperonin 60RNA, Messenger

Identifiers

PMID41779859
PMCPMC12959401

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.