Evidence map›Paper›PMID 41779860›Full record

ArticleScience advances2026

Cis-regulatory evolution reveals sensory trade-offs as a genetic basis for temporal niche evolution in tapirs.

Xiaofang Zhou, Deng Pan, Jiong Zhou, Wu Chen, Ge Han, Ru Zhang, Chen Wang, Yifan Mao, Zecheng Du, Fenglei Zhang and 13 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Xiaofang ZhouSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0009-0002-2491-132X
Deng PanBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory for Ophthalmic Cell and Gene Therapy, Beijing 100730, China.ORCID 0009-0000-1482-6100
Jiong ZhouSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0009-0003-2730-5023
Wu ChenGuangzhou Zoo and Guangzhou Wildlife Research Center, Guangzhou 510070, China.ORCID 0000-0002-4033-254X
Ge HanSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0000-0002-1104-1962
Ru ZhangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling 712100, China.ORCID 0000-0003-3216-2787
Chen WangGuangzhou Zoo and Guangzhou Wildlife Research Center, Guangzhou 510070, China.ORCID 0000-0001-6711-7420
Yifan MaoSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.
Zecheng DuSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.
Fenglei ZhangSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0009-0003-3957-3420
Huishan YueSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.
Jinrui MaSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0009-0005-6418-5045
Zihe LiSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.
Ren-Juan ShenBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory for Ophthalmic Cell and Gene Therapy, Beijing 100730, China.
Bao WangSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.
Wenbo ZhuSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0000-0002-4991-9021
Yingmei PengSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0009-0007-8307-2737
Kangxin JinBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory for Ophthalmic Cell and Gene Therapy, Beijing 100730, China.ORCID 0000-0002-0108-6948
Dong-Dong WuState Key Laboratory of Genetic Evolution and Animal Models, Kunming Natural History Museum of Zoology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.ORCID 0000-0001-7101-7297
Wen WangSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0000-0002-7801-2066
Botong ZhouSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0000-0002-1091-5867
Zi-Bing JinBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory for Ophthalmic Cell and Gene Therapy, Beijing 100730, China.ORCID 0000-0003-0515-698X
Lei ChenSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710072, China.ORCID 0000-0003-3989-9239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evolutionary shifts in diel activity patterns shape sensory remodeling across mammals, yet the genetic basis remains poorly understood. Tapirs represent a unique natural experiment, having reverted from a cathemeral ancestor to a nocturnal niche characterized by reduced vision but enhanced hearing and olfaction. Here, we investigate the genetic basis of this phenomenon by generating high-quality chromosome-level genomes for

Indexed as

Biological EvolutionEvolution, MolecularRegulatory Sequences, Nucleic AcidAnimalsMice

Identifiers

PMID41779860
PMCPMC12959415

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.