ArticleThe Journal of international medical research2026
Vitamin D status in relation to lower extremity arterial plaque and diabetic foot ulcers in type 2 diabetes.
Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
ObjectivesLimited evidence exists regarding the association of vitamin D status with lower extremity arterial plaque progression and diabetic foot ulcer outcomes. This study investigated the relationship between vitamin D status and the risk of lower extremity arterial plaque progression and diabetic foot ulcer development.MethodsIn this cross-sectional analysis of 7476 consecutively hospitalized type 2 diabetes patients (2018-2024), serum 25-hydroxyvitamin D level was measured using the electrochemiluminescence method. Vitamin D deficiency (<20 ng/mL) and insufficiency (20-30 ng/mL) were defined per the Endocrine Society guidelines. Lower extremity arterial plaque was identified using arterial Doppler ultrasonography, and diabetic foot ulcer was diagnosed using the International Working Group on the Diabetic Foot 2019 criteria. Multivariate logistic regression and receiver operating characteristic analyses were used to evaluate associations between parameters.ResultsDecreased 25-hydroxyvitamin D levels were correlated with adverse lipid profiles (high-density lipoprotein cholesterol: r = 0.152,
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