Evidence map›Paper›PMID 41780929›Full record

ArticleBiomacromolecules2026

Routine Direct Quantification of Methacrylic Groups per Gelatin Unit in Gelatin Methacryloyl Using Ultraviolet Spectroscopy.

Nazar Rad, Zuzanna Stasiak, Marta Klak, Michał Wszoła, Sylwester Domański

Abstract read
In one paragraph

Article in Biomacromolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nazar RadPolbionica SA, Aleja Prymasa Tysiaclecia 79A, Warsaw 01-242, Poland.ORCID 0000-0002-2755-8085
Zuzanna StasiakPolbionica SA, Aleja Prymasa Tysiaclecia 79A, Warsaw 01-242, Poland.
Marta KlakPolbionica SA, Aleja Prymasa Tysiaclecia 79A, Warsaw 01-242, Poland.
Michał WszołaPolbionica SA, Aleja Prymasa Tysiaclecia 79A, Warsaw 01-242, Poland.
Sylwester DomańskiPolbionica SA, Aleja Prymasa Tysiaclecia 79A, Warsaw 01-242, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gelatin methacryloyl (GelMA) is an essential biomaterial for 3D bioprinting due to its excellent biocompatibility and easily tunable physical properties. GelMA quality strongly depends on the number of methacrylic groups introduced during the synthesis. We present a direct UV assay for routine quantification of methacrylic groups in GelMA. The accuracy and precision of the method are comparable to those of NMR techniques. Moreover, the method is independent of sample concentration and adapted for gelatin from various sources. Additionally, we developed a UV-based method for determining methacrylic acid in GelMA and demonstrated how methacrylic acid contamination affects the quantification of methacrylic groups. Rather than reporting the degree of substitution alone, we define the methacrylic content as the quantity of methacrylic groups per 100 kDa gelatin unit, which makes the metric independent of the number of lysine residues in gelatin. This routine-ready approach lowers the barrier to reliable GelMA characterization and standardizes reporting across batches and laboratories.

Indexed as

Biocompatible MaterialsGelatinMethacrylatesSpectrophotometry, UltravioletBiocompatible MaterialsGelatingelatin methacryloylMethacrylatesmethacrylic acid

Identifiers

PMID41780929
PMCPMC13080777

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.