Evidence map›Paper›PMID 41781323›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2026

Functional Clusters for Shape, Texture, and Motion Encoding in Macaque V2.

Taekjun Kim, Rohit Kamath, Gaku Hatanaka, Tomoyuki Namima, Celeste Dylla, Wyeth Bair, Anitha Pasupathy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Curvature tuning in areas V2 and V4 of the developing macaque.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Taekjun KimDepartment of Neurobiology & Biophysics and Washington National Biomedical Research Center, University of Washington, Seattle, Washington 98195 taekjun@uw.edu pasupat@u.washington.edu.ORCID https://orcid.org/0000-0002-8376-8861
Rohit KamathDepartment of Neurobiology & Biophysics and Washington National Biomedical Research Center, University of Washington, Seattle, Washington 98195.
Gaku HatanakaDepartment of Neurobiology & Biophysics and Washington National Biomedical Research Center, University of Washington, Seattle, Washington 98195.
Tomoyuki NamimaGraduate School of Frontier Biosciences, The University of Osaka and Center for Information and Neural Networks, National Institute of Information and Communications Technology, Suita 565-0871, Japan.ORCID https://orcid.org/0000-0002-0914-3599
Celeste DyllaDepartment of Neurobiology & Biophysics and Washington National Biomedical Research Center, University of Washington, Seattle, Washington 98195.
Wyeth BairDepartment of Neurobiology & Biophysics and Washington National Biomedical Research Center, University of Washington, Seattle, Washington 98195.ORCID https://orcid.org/0009-0008-4642-8447
Anitha PasupathyDepartment of Neurobiology & Biophysics and Washington National Biomedical Research Center, University of Washington, Seattle, Washington 98195 taekjun@uw.edu pasupat@u.washington.edu.ORCID https://orcid.org/0000-0003-3808-8063

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Vision Research CoreP30EY001730 · NEI · UNIVERSITY OF WASHINGTON · PI JAMES Bryant HURLEY · 1985 to 2026
$23.5M
The role of area V4 in the perception and recognition of visual objectsR01EY018839 · NEI · UNIVERSITY OF WASHINGTON · PI Anitha Pasupathy · 2009 to 2026
$9.0M
Integrative circuit dissection in the behaving nonhuman primateU01NS131810 · NINDS · UNIVERSITY OF WASHINGTON · PI BAIR, WYETH DANIEL, PASUPATHY, ANITHA · 2023 to 2025
$3.1M
Spatiotemporal representation in ventral visual pathwayR01EY029601 · NEI · UNIVERSITY OF WASHINGTON · PI PASUPATHY, ANITHA · 2021 to 2025
$2.3M
NEI NIH HHS P30 EY001730NEI NIH HHS R01 EY018839NEI NIH HHS R01 EY029601NIH HHS P51 OD010425NINDS NIH HHS U01 NS131810
6 · The paper itself

Abstract

Macaque primary visual cortex (V1) exhibits exquisite columnar organization, while midlevel area V4 does not. Here we investigated the functional organization and representational bases of intervening area V2 in three macaques (one male, two females) with high-density Neuropixels recordings and a variety of visual stimuli-shape, texture, drifting grating, and translational motion patches. We observed dense clusters of similarly tuned neurons often spanning ∼500 µm, consistent with a columnar structure. In terms of representational bases, V2 responses were largely explained by stimulus features based on local image statistics: shape tuning is well modeled by a linear combination of orientation filters, and direction selectivity is stronger with surface compared with object motion, in striking contrast to V4. Overall, our results support the progression from columns to sparse clusters as neuronal representations transform from encoding local features and feature conjunctions in V1/V2 to a high-dimensional object-based code in V4.

Indexed as

Form PerceptionMotion PerceptionNeuronsPattern Recognition, VisualPrimary Visual CortexVisual CortexAnimalsFemaleMacaca mulattaMalePhotic StimulationVisual Pathwayscortical columnfunctional architectureimage statisticsmonkeyNeuropixelsvisual hierarchy

Identifiers

PMID41781323
PMCPMC13055134

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.