ArticleNature2026
Lipid metabolism drives dietary effects on T cell ferroptosis and immunity.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026Review
- Ferroptotic propagation: from single-cell execution to tissue-scale death programs.Cell research · 2026Review
- Subcellular regulation of ferroptosis: roles of individual intracellular organelles and cross talk.American journal of physiology. Cell physiology · 2026Review
- Ferroptosis in T cells: mechanisms, biology and translational opportunities.Nature reviews. Immunology · 2026Review
- FATP2-mediated lipid metabolism enhances chimeric antigen receptor T-cell therapy resistance in B-cell acute lymphoblastic leukemia.Leukemia · 2026Article
- Iron-ing out ferroptosis-mediated T cell dysfunction in cancer.Nature cancer · 2026Article
- Article
- Acyl-CoA thioesterases and their derived lipid mediators: linking Acyl-CoA metabolic reprogramming to the tumor microenvironment.Frontiers in immunology · 2026Review
- Mechanistic insights into ferroptosis and its therapeutic potential in hepatocellular carcinoma.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
40 authors.
Naiqi Wang *Frazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-2554-4819
Zhian Chen *Frazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0003-0073-2941
Yin Yao *Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chenglong Sun *Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.ORCID http://orcid.org/0000-0002-4684-9603
Wei Wei *State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-6244-3187
Lei Sun *Department of Endocrinology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China.
Hao Zhang *Laboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.ORCID http://orcid.org/0000-0003-3887-6158
Feng Li *State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-0045-1501
Daniel ButcherFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-3420-5421
Shi-Ran SunDepartment of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jialei GongFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Yingxin Celia JiangHeart Research Institute, The University of Sydney, Sydney, New South Wales, Australia.
Yanfei QiHeart Research Institute, The University of Sydney, Sydney, New South Wales, Australia.
Jingxuan HuangFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0003-3849-319X
Sam NettelfieldFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-7786-7660
Rui LiuFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Xiaoyue ZhengDepartment of Endocrinology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China.
Chenyu LiDepartment of Endocrinology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China.
Yang FuDepartment of Endocrinology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China.
Haoyuan GengKey Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Limin ZhaoFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-6144-6458
Hongjian SunFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Yang YangFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-4840-3023
Yexin GeSchool of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID http://orcid.org/0009-0008-0207-3613
Mehrdad PazhouhandehFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0001-5433-9606
Christopher K BarlowMonash Proteomics and Metabolomics Platform, Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.
Katherine Joanna JeppeMonash Proteomics and Metabolomics Platform, Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0003-2284-5090
Joseph YunisFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-0272-0605
Chen ZhuFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Yunbo WeiLaboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.ORCID http://orcid.org/0000-0003-3643-9106
Xiaowen LiangFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Kim BridleGallipoli Medical Research, Greenslopes Private Hospital, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-7090-1387
David M FrazerQIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0003-4098-1379
Siok-Keen TeyFaculty of Health, Medicine and Behaviour Sciences, University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0001-9567-382X
Yuhua LiDepartment of Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Zhaohui YangHubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Minda Hospital of Hubei Minzu University, Enshi, China.
Minglei ShuShandong Artificial Intelligence Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Zheng LiuDepartment of Otorhinolaryngology-Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID http://orcid.org/0000-0002-4168-6702
Darrell CrawfordGallipoli Medical Research, Greenslopes Private Hospital, Brisbane, Queensland, Australia.
Di YuFrazer Institute, Faculty of Health, Medicine and Behaviour Sciences, The University of Queensland, Brisbane, Queensland, Australia. di.yu@uq.edu.au.ORCID http://orcid.org/0000-0003-1721-8922
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ferroptosis, a major mechanism of non-apoptotic programmed cell death, critically regulates the homeostasis and functionality of peripheral CD4
Indexed as
DietFerroptosisLipid MetabolismT-LymphocytesAnimalsCD8-Positive T-LymphocytesCoenzyme A LigasesFatty Acids, MonounsaturatedFatty Acids, UnsaturatedFemaleHomeostasisHumansImmunity, HumoralMaleMiceMice, Inbred C57BLAcsl4 protein, mouseCoenzyme A LigasesFatty Acids, MonounsaturatedFatty Acids, Unsaturatedglutathione peroxidase 4, mousePhospholipid Hydroperoxide Glutathione PeroxidasePhospholipids
Identifiers
PMID
41781622What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.