SynthesisBMC geriatrics2026
Feasibility of high intensity exercise training in people with dementia and Mild Cognitive Impairment: a systematic review.
Synthesis in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe number of people with dementia is around 50 million worldwide and this number is expected to grow in the coming decades. To date, scientific evidence suggests that physical activity is an encouraging aid in slowing down the progression of dementia and has positive effects on many aspects: metabolic, independence in activities of daily living (ADLs), cognitive and muscle strength. However, few studies analyze the feasibility and the effects of high-intensity exercise programs in people with dementia. The aim is to synthesize evidence on the feasibility of high-intensity exercise training (HIET) in people with dementia and/or Mild Cognitive Impairment (MCI) and to evaluate its effects on cognition, physical performance, ADLs, neuropsychiatric symptoms and quality of life.
methodsClinical trials and RCTs published up to March 2025 were selected through searches in PubMed, Scopus and Google Scholar, using MeSH terms related to dementia and high-intensity physical exercise. Studies involving people with dementia and/or MCI undergoing high-intensity aerobic and/or strength training were included. Methodological quality was assessed using the PEDro scale, and risk of bias was evaluated with the Cochrane RoB 2 tool.
results21 studies met inclusion criteria, including participants with dementia and/or MCI. Feasibility was generally supported and the dropout rate was 13% with high adherence to the programs. Regarding effectiveness, HIET showed cognitive improvements in some studies, while others reported no significant effects. Physical performance, such as walking speed and balance, improved, but there were no significant changes in activities of daily living or quality of life.
conclusionsThe results of the literature analyzed show that HIET can be proposed to this population, furthermore it benefits on many parameters of interest. It can be concluded that HIET could be taken into consideration for training people with dementia and/or MCI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.