Evidence map›Paper›PMID 41781982›Full record

ReviewMicrobial cell factories2026

Bioactivities and biosynthesis of monoterpene-based biopesticides: current state and perspectives.

Ruiqi Chen, Weilin Liu, Daoguang Tian, Shengli Wang, Jianjun Qiao, Weiguo Li, Qinggele Caiyin

Abstract readReview
In one paragraph

Review in Microbial cell factories, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruiqi Chen *School of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, 300072, China.
Weilin Liu *School of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, 300072, China.
Daoguang TianSchool of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, 300072, China.
Shengli WangSchool of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, 300072, China.
Jianjun QiaoSchool of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, 300072, China.
Weiguo LiSchool of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, 300072, China. liweiguo@tju.edu.cn.
Qinggele CaiyinSchool of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, 300072, China. qinggele@tju.edu.cn.

Funding

"Pioneer" and "Leading Goose" R&D Program of Zhejiang 2025C01094Zhejiang Provincial Natural Science Foundation of China LQN25C010006
6 · The paper itself

Abstract

Biopesticides constitute a category of natural products and organisms effective against pests. Given their advantages, such as easier clearance and degradation compared to chemical pesticides, along with their lack of detrimental effects on ecosystem health, they represent a promising alternative for sustainable pest management and crop protection. The development of natural biopesticides to substitute synthetic pesticides is therefore of paramount importance for securing food safety and advancing agricultural production. Monoterpenes, primarily present in plant volatile oils, are characterized by a strong aroma and a range of biological activities-including insecticidal, antimicrobial, antiviral, anti-inflammatory, antioxidant, antitumor, and anticancer effects. This profile renders them a promising platform for the research and development of new, more effective pesticides. This article reviews the biosynthetic pathways of monoterpenes and contemporary engineering strategies for their microbial synthesis. Additionally, an evolutionary analysis database for monoterpene synthases (MTPS) has been established. Finally, the biological activities of monoterpenes are summarized and analyzed, with particular emphasis on their potential and advantages as biopesticides, thereby providing direction for the future development of monoterpene-based biopesticides.

Indexed as

Biological Control AgentsMonoterpenesAnti-Infective AgentsBiosynthetic PathwaysInsecticidesIntramolecular LyasesOils, VolatileAnti-Infective AgentsBiological Control AgentsInsecticidesIntramolecular LyasesMonoterpenesOils, Volatilepinene cyclase IBioactivitiesBiosynthesisMonoterpene-based biopesticidesSynthetic biology

Identifiers

PMID41781982
PMCPMC13067451

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.