Evidence map›Paper›PMID 41782152›Full record

Trial reportBMC medicine2026

Effects of ultrasound-guided stellate ganglion block in poststroke bulbar palsy: a double-blind placebo-controlled trial.

Hongji Zeng, Weihong Zhang, Ying Yang, Yi Li, Siyu Wang, Lixuan Fang, Changming Wen, Weijia Zhao, Dongjian Li, Siyu Luo and 7 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06319534 (A Randomized Controlled Study to Explore the Effect of Stellate Ganglion Block in Dysphagic Patients With Bulbar Palsy After Ischemic Stroke), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06319534 nacompletednot on this map

A Randomized Controlled Study to Explore the Effect of Stellate Ganglion Block in Dysphagic Patients With Bulbar Palsy After Ischemic Stroke

TypeinterventionalSponsorZeng XiRan2024 to 2025Enrolled124ConditionsBulbar PalsyArmsComprehensive rehabilitation, Stellate ganglion block, Lidocaine Hydrochloride, placebo injection
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Hongji ZengSchool of Health Policy and Management, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, 100000, China.
Weihong ZhangDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Ying YangDepartment of Rehabilitation Medicine, The People's Hospital of Suzhou New District, Suzhou, 215000, China.
Yi LiDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Siyu WangDepartment of Rehabilitation Medicine, The Geriatrics Hospital of Heilongjiang Province, Harbin, 150000, China.
Lixuan FangDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 440100, China.
Changming WenDepartment of Neurology, Nanyang Central Hospital, Nanyang, 473005, China.
Weijia ZhaoSchool of Public Health, Zhengzhou University, Zhengzhou, 450000, China.
Dongjian LiDepartment of Rehabilitation Medicine, Lankao First Hospital, Kaifeng, 475399, China.
Siyu LuoPeabody College, Vanderbilt University, Nashville, TN, 37240, USA.
Jing ZengDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Xin'ao WangDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Pengchao LuoDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Heping LiDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Liugen WangDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Chen WangDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China. wangchen@126.com.
Xi ZengDepartment of Rehabilitation Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China. zengxizdyfy@126.com.

Funding

The Special Project of Research and Development of the Science and Technology Department in Henan Province 241111310600
6 · The paper itself

Abstract

backgroundBulbar palsy typically causes severe dysphagia. Based on rehabilitation interventions, stellate ganglion block (SGB) might improve swallowing function by regulating sympathoexcitation and cerebral perfusion. This study explored the short- and long-term effects of SGB on swallowing function, anxiety, and cerebral blood flow in patients with bulbar palsy after ischemic stroke.

methodsThis randomized double-blind placebo-controlled trial included 124 participants in rehabilitation departments from March 2024 to July 2025 in China. The participants were randomized 1:1 to SGB or placebo groups, and all received routine treatment for 10 consecutive days. The SGB group received SGB with lidocaine hydrochloride, whereas the placebo group received block with normal saline. The primary outcome was the clinical severity of dysphagia. The secondary outcomes were airway protection, forward and upward movement distances of the hyoid bone, accumulation of secretions, pharyngeal residue, anxiety, and mean blood flow velocity (V

resultsThere were no significant baseline inter-group differences. After treatment, significant (P < 0.001) interaction effects were observed for dysphagia severity (η

conclusionsIn patients with bulbar palsy after ischemic stroke who receive routine treatment, SGB is safe and can effectively improve swallowing function, airway protection, and anxiety. The effects of SGB on vertebral artery blood flow are temporary, but the functional impacts are long-term.

trial registrationClinicalTrials.gov. (Unique identifier: NCT06319534, 20/03/2024).

Indexed as

Autonomic Nerve BlockBulbar Palsy, ProgressiveIschemic StrokeStellate GanglionStrokeAdultAgedDeglutition DisordersDouble-Blind MethodFemaleHumansLidocaineMaleMiddle AgedTreatment OutcomeLidocaineIschemic strokeLateral medullary syndromeRehabilitationSympathetic nerve blockWallenberg syndrome

Identifiers

PMID41782152
PMCPMC13067633

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.