Evidence map›Paper›PMID 41782235›Full record

ArticleRenal failure2026

Muscle weakness, pain, and fatigue impair daily function in chronic kidney disease: a cross-sectional analysis from the I-RACE study.

Roseanne E Billany, Heitor S Ribeiro, Courtney J Lightfoot, Thomas J Wilkinson, Alice C Smith, Matthew P M Graham-Brown, Emma L Watson

Abstract read
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Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roseanne E BillanyDivision of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Heitor S RibeiroUniversity of Brasília, Faculty of Health Sciences, Brasília, Federal District, Brazil.
Courtney J LightfootDivision of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Thomas J WilkinsonNIHR Leicester Biomedical Research Centre, University of Leicester and University Hospitals of Leicester NHS Trust, UK.
Alice C SmithLeicester Partnership for Kidney Health Research, University of Leicester, Leicester, UK.
Matthew P M Graham-BrownDivision of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Emma L WatsonDivision of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle dysfunction symptoms such as weakness and cramps are common in people with chronic kidney disease (CKD), but their impact on activities of daily living (ADLs) is not well understood. This study explored the association between muscle symptoms and patient-reported ADL impact in individuals with and without CKD. This cross-sectional secondary analysis of the I-RACE study (ISRCTN11596292) included adults (≥18 years) across the CKD spectrum and adults without CKD. Participants completed a bespoke Muscle Symptoms Scale assessing muscle-related symptoms and their impact on ADLs (daily activities, socializing, working, exercising). Group differences were tested using univariate general linear models; associations were examined

Indexed as

Activities of Daily LivingFatigueMuscle WeaknessPainRenal Insufficiency, ChronicAdultAgedCross-Sectional StudiesFemaleHumansKidney TransplantationMaleMiddle AgedRenal DialysisSymptom Burdendialysiskidney failuremusculoskeletal painNeuromuscular manifestations

Identifiers

PMID41782235
PMCPMC12964459

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.