Evidence map›Paper›PMID 41782309›Full record

ReviewIntegrative cancer therapies

The Effect of a Ketogenic Diet on Cancer: Evidence From Systematic Reviews and Meta-Analyzes.

Majid Kamali, Masoomeh Ataei Kachooei, Bahareh Aminnezhad, Elham Nikoei Foshtomi, Alireza Eftekhar, Ali Shamsi-Goushki, Saeideh Mohammadi, Ali Nouri, Mohammad Esmail Akbari, Mona Zendehdel and 8 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Majid KamaliTabriz University of Medical Sciences, Iran.
Masoomeh Ataei KachooeiIsfahan University of Medical Sciences, Iran.
Bahareh AminnezhadIslamic Azad University, Tehran, Iran.
Elham Nikoei FoshtomiUniversidade da Coruña, Spain.
Alireza EftekharAhvaz Jundishapur University of Medical Sciences, Iran.
Ali Shamsi-GoushkiMashhad University of Medical Sciences, Iran.
Saeideh MohammadiShahid Beheshti University of Medical Sciences, Tehran, Iran.
Ali NouriTehran University of Medical Sciences, Iran.
Mohammad Esmail AkbariShahid Beheshti University of Medical Sciences, Tehran, Iran.
Mona ZendehdelAhvaz Jundishapur University of Medical Sciences, Iran.
Bita MoradiKermanshah University of Medical Sciences, Iran.
Narjes Ashouri MirsadeghiShahid Beheshti University of Medical Sciences, Tehran, Iran.
Parsa BahmaniShahid Beheshti University of Medical Sciences, Tehran, Iran.
Farnush BakhshimoghaddamAhvaz Jundishapur University of Medical Sciences, Iran.
Razieh BahiraieShahid Beheshti University of Medical Sciences, Tehran, Iran.
Hamid AbbasiTabriz University of Medical Sciences, Iran.
Saeid DoaeiShahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0009-0008-7193-5117
Maryam GholamalizadehShahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmerging evidence suggests that the ketogenic diet (KD) may support cancer treatment by improving metabolic parameters and reducing treatment-related side effects. This review aimed to synthesize evidence from systematic reviews and meta-analyses on the effects of ketogenic diets in cancer, focusing on metabolic outcomes, body composition, quality of life, and tumor progression. Treatment-related complications were considered as exploratory outcomes.

methodsA comprehensive review of meta-analyses were conducted following PRISMA guidelines. Databases including PubMed, Scopus, and Web of Science were searched for systematic reviews and meta-analyses exploring the effects of KD on cancer and treatment side effects. After screening 615 articles, 24 eligible reviews were examined to explore the effects of ketogenic diets on metabolism, quality of life, body composition, and cancer progression.

resultsKD improved metabolic markers such as glucose and triglycerides, and showed benefits in body composition and quality of life. Evidence on treatment-related complications, including radiotherapy side effects, was limited and heterogeneous.

conclusionsKD shows promise as a safe and effective adjunctive therapy in cancer management. More evidence is needed to draw firm conclusions.

Indexed as

Diet, KetogenicNeoplasmsBody CompositionHumansQuality of Lifecancerketogenic dietradiotherapyside effect

Identifiers

PMID41782309
PMCPMC12966578

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.