Evidence map›Paper›PMID 41782739›Full record

ReviewFrontiers in radiology2026

Neuroimaging of neonatal brain post therapeutic hypothermia: a practical guide to the non-pediatric neuroradiologist.

Martina Di Stasi, Angela Plantulli, Felicia Filomena Varsalone, Gianpiero Locatelli, Chiara Paolella, Giulia Frauenfelder, Margherita Di Stasi, Francesco Taglialatela, Maria Grazia Corbo, Daniele Giuseppe Romano

Abstract readReview
In one paragraph

Review in Frontiers in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Martina Di StasiDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Angela PlantulliDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Felicia Filomena VarsaloneDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Gianpiero LocatelliDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Chiara PaolellaDepartment of Pediatric Neurosciences, Neuroradiology, Azienda Ospedaliera di Rilievo Nazionale Santobono Pausilipon, Naples, Italy.
Giulia FrauenfelderDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Margherita Di StasiOphthalmology Unit, Presidio Ospedaliero San Luca, Vallo Della Lucania, Italy.
Francesco TaglialatelaDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Maria Grazia CorboDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Daniele Giuseppe RomanoDepartment of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic hypothermia is currently considered the standard treatment for neonates diagnosed with moderate or severe hypoxic ischemic encephalopathy in high-resource settings, improving survival rates and reducing long-term disability. Consequently, this treatment is increasingly performed in non-pediatric hospitals with intensive neonatal care units. Magnetic resonance imaging plays a fundamental role in assessing the extent of brain injury and represents a key prognostic tool in these patients who present to the neuroradiologist with critical care condition. As the current literature on this topic is flourishing, in this study, we aim to provide a practical guide to the non-pediatric neuroradiologist by summarizing protocols, characteristic radiological findings, and recommendations for ensuring optimal imaging timing by revising published studies.

Indexed as

hypoxic ischemic encephalopathy (HIE)magnetic resonance imaging (MRI)neonatal brainnon-pediatric neuroradiologisttherapeutic hypothermia (TH)

Identifiers

PMID41782739
PMCPMC12953461

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.