ArticleVascular health and risk management2026
Postoperative Blood Glucose Trajectories are Associated with Inflammatory Markers and Functional Outcomes in Acute Ischemic Stroke Treated by Thrombectomy.
Article in Vascular health and risk management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To describe postoperative blood glucose trajectories in patients with acute ischemic stroke treated by mechanical thrombectomy (MT) and to examine their associations with 90-day functional outcomes and early postoperative inflammatory markers. Patients and Methods: This retrospective cohort study included 150 patients who underwent MT for large vessel occlusion (LVO) stroke between March 2023 and September 2024. Daily capillary blood glucose levels (fasting and postprandial) were recorded for seven days post-procedure, and linear regression was used to calculate individual postoperative glucose slopes. Patients were classified into a Glucose-Increasing Group or Glucose-Decreasing Group based on the median slope. The primary outcome was the 90-day modified Rankin Scale (mRS). Secondary outcomes included postoperative day-1 levels of C-reactive protein (CRP), interleukin-6 (IL-6), and interleukin-10 (IL-10). Statistical analyses included group comparisons and multivariate logistic regression adjusting for potential confounders. Results: Patients in the Glucose-Increasing Group had significantly higher median 90-day mRS scores compared with the Glucose-Decreasing Group (4.0 vs 3.0; P = 0.030). They also exhibited higher postoperative inflammatory markers: CRP (5.2 vs 4.1 mg/L; P = 0.022), IL-6 (6.9 vs 5.7 pg/mL; P = 0.015), and IL-10 (134 vs 104 pg/mL; P = 0.0017). However, in multivariate logistic regression, glucose trajectory was not an independent predictor of poor outcome (mRS ≥ 3; OR 0.67, 95% CI 0.34-1.37; P = 0.272). Conclusion: An increasing postoperative blood glucose trend is associated with higher early inflammatory marker levels and poorer 90-day functional outcomes in LVO stroke patients undergoing thrombectomy. Although not an independent predictor after adjustment, postoperative glycemic trajectory may reflect underlying metabolic and inflammatory stress. Prospective studies are needed to further clarify these relationships.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.