Evidence map›Paper›PMID 41783777›Full record

ArticleTherapeutic advances in medical oncology2026

The differences of pelvic lymph node metastasis between squamous cell carcinoma and adenocarcinoma in early-stage cervical cancer patients undergoing radical surgery and adjuvant radiotherapy: a large cohort study.

Zheng Miao, Xi-Lin Yang, Jia-Wei Zhu, Yun-Can Zhou, Hui Guan, Jun-Fang Yan, Peng Peng, Fu-Quan Zhang

Abstract read
In one paragraph

Article in Therapeutic advances in medical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zheng MiaoDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Xi-Lin YangDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Jia-Wei ZhuDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Yun-Can ZhouDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Hui GuanDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Jun-Fang YanDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, China.ORCID https://orcid.org/0009-0006-2624-9869
Peng PengDepartment of Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, China.
Fu-Quan ZhangDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, China.ORCID https://orcid.org/0009-0003-8643-8862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The differences in lymph node metastasis (LNM) between patients with early-stage squamous cell carcinoma (SCC) and adenocarcinoma (ADC) cervical cancer remained to be clarified. Objectives: To compare the differences of LNM between early-stage SCC and ADC cervical cancer patients receiving radical surgery and adjuvant radiotherapy. Designs: A retrospective large cohort study. Methods: The pelvic LNM rate was estimated and compared. Univariate and multivariate logistic regression analyses were applied to identify the risk factors for pelvic LNM. The cumulative survival rates were estimated and compared with Kaplan-Meier methods and log-rank test, respectively. The propensity score matching (PSM) was utilized for adjustment of baseline characteristics. Results: A total of 577 cervical cancer patients were included in the analysis. Pelvic LNM could be observed in 22.7% (51/225) of ADC and 25.9% (91/352) of SCC patients ( Conclusion: No significant difference in pelvic LNM rate was observed between ADC and SCC patients. The presence of LNM seemed to further impair the oncological outcomes for ADC while not for SCC patients. Consolidate chemotherapy appeared to improve the DFS for SCC while not for ADC patients.

Indexed as

cervical cancerconsolidate chemotherapyearly stagelymph node metastasisradical surgery

Identifiers

PMID41783777
PMCPMC12954041

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.