ArticleFrontiers in nutrition2026
Effects of time-restricted eating on weight loss, sleep, and quality of life in obstructive sleep apnea-hypopnea syndrome (OSAHS) patients with obesity: a randomized controlled trial.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Weight loss is a key adjunctive therapy for obstructive sleep apnea-hypopnea syndrome (OSAHS) patients with obesity; however, its long-term success rate remains low. Time-restricted eating (TRE) is an emerging dietary strategy for weight-loss, but its application in obese OSAHS patients is still limited. This study aimed to evaluate the effects of TRE on weight loss, sleep, and quality of life (QoL) in obese OSAHS patients. Methods: In this randomized controlled trial, 68 obese adults with OSAHS were allocated (1:1) to an 8-h TRE group (eating window: 10 a.m. to 6 p.m.) or a control group receiving standard care for 12 weeks. The primary outcomes were changes in body mass index (BMI) and sleep quality (Pittsburgh Sleep Quality Index, PSQI). Secondary outcomes included changes in daytime sleepiness (Epworth Sleepiness Scale, ESS), QoL (Calgary Sleep Apnea Quality of Life Index, SAQLI), and OSAHS risk (STOP-Bang questionnaire, SBQ). Results: Sixty participants completed the study. At 12 weeks, while the between-group difference in BMI change was not significant [adjusted mean difference (MD): -0.18 kg/m Conclusion: A 12-week 8-h TRE intervention effectively induced weight loss and improved specific aspects of sleep and QoL in obese patients with OSAHS. TRE shows promise as a beneficial dietary intervention within the comprehensive management of OSAHS and obesity.
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