ReviewMedical review (2021)2026
Regulatory roles of bioactive lipids in vascular homeostasis and remodeling.
Review in Medical review (2021), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioactive lipids are low-abundance, rapidly acting signaling molecules that orchestrate vascular homeostasis and remodeling through a closed-loop cycle of synthesis, localization, receptor/effector sensing, and inactivation. This review delineates the major bioactive lipid classes - eicosanoids, lysophospholipids, sphingolipids, and sterol-derived mediators - linking their enzymatic pathways, transport mechanisms, receptor networks, and termination routes to vascular physiology and disease. Centered on vascular homeostasis and remodeling, we summarize the roles of bioactive lipids across atherosclerosis, aneurysms, hypertension, and thrombosis. Collectively, these findings underscore the pivotal role of bioactive lipid signaling in cardiovascular disease, suggesting that these pathways and receptors may serve as promising targets for diagnosis and therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.