Evidence map›Paper›PMID 41783928›Full record

ArticleACS applied materials & interfaces2026

Sustainable Eggshell-Based Amorphous Calcium Phosphate Scaffolds and Membrane Protein Hydrogel for Regeneration in Rabbit Femoral and Calvarial Defects.

Qianli Ma, Katrin Anja Staudigel, Kristaps Rubenis, Zhaoyue Fu, Torben Hildebrand, Markuss Zaldenieks, Ólafur Eysteinn Sigurjónsson, Liebert Parreiras Nogueira, Janis Locs, Dagnija Loca and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qianli MaDepartment of Biomaterials, Faculty of Dentistry, University of Oslo, Oslo 0317, Norway.
Katrin Anja StaudigelDepartment of Biomaterials, Faculty of Dentistry, University of Oslo, Oslo 0317, Norway.
Kristaps RubenisInstitute of Biomaterials and Bioengineering, Faculty of Natural Sciences and Technology, Riga Technical University, Paula Valdena Street 3 k-1, Riga LV-1048, Latvia.ORCID 0000-0002-9044-8479
Zhaoyue FuDepartment of Immunology, School of Basic Medicine, Air Force Medical University, Xi'an 710032, P. R. China.
Torben HildebrandDepartment of Biomaterials, Faculty of Dentistry, University of Oslo, Oslo 0317, Norway.
Markuss ZaldenieksInstitute of Biomaterials and Bioengineering, Faculty of Natural Sciences and Technology, Riga Technical University, Paula Valdena Street 3 k-1, Riga LV-1048, Latvia.
Ólafur Eysteinn SigurjónssonSchool of Science and Engineering, Reykjavík University, Reykjavík 102, Iceland.
Liebert Parreiras NogueiraOral Research Laboratory, Faculty of Dentistry, University of Oslo, Oslo 0317, Norway.
Janis LocsInstitute of Biomaterials and Bioengineering, Faculty of Natural Sciences and Technology, Riga Technical University, Paula Valdena Street 3 k-1, Riga LV-1048, Latvia.ORCID 0000-0003-3162-7431
Dagnija LocaInstitute of Biomaterials and Bioengineering, Faculty of Natural Sciences and Technology, Riga Technical University, Paula Valdena Street 3 k-1, Riga LV-1048, Latvia.
Lihua ChenDepartment of Immunology, School of Basic Medicine, Air Force Medical University, Xi'an 710032, P. R. China.
Håvard Jostein HaugenDepartment of Biomaterials, Faculty of Dentistry, University of Oslo, Oslo 0317, Norway.ORCID 0000-0002-6690-7233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critical-sized bone defects require grafts with ideal spatial supporting. We upcycled eggshell waste sustainably into porous amorphous calcium phosphate (ACP) scaffolds and evaluated their early bone-regeneration performance alone and in combination with flexible and bioactive adjuncts

Indexed as

Bone RegenerationCalcium PhosphatesEgg ProteinsEgg ShellFemurHydrogelsMembrane ProteinsSkullTissue ScaffoldsAnimalsPorosityRabbitsamorphous calcium phosphateCalcium PhosphatesEgg ProteinsHydrogelsMembrane Proteinsamorphous calcium phosphatebone regenerationcritical-sized bone defecteggshellporous scaffold

Identifiers

PMID41783928
PMCPMC13006942

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.