ArticleJournal of bacteriology2026
Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in
Evan J Pardue, Tengfei Zhong, Nichollas E Scott, Biswanath Jana, Wandy Beatty, Juan C Ortiz-Marquez, Mohammed Kaplan, Clay Jackson-Litteken, Mario F Feldman
Abstract read
In one paragraphArticle in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Evan J Pardue *Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-3576-7901 Nichollas E Scott *Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0003-2556-8316 Biswanath Jana *Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Wandy Beatty *Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Juan C Ortiz-Marquez *Biology Department, Boston College, Chestnut Hill, Massachusetts, USA.
Mohammed Kaplan *Department of Microbiology, University of Chicago, Chicago, Illinois, USA.
Clay Jackson-Litteken *Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Mario F Feldman *Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-4497-0976 Funding
In situ investigation of bacterial secretion systems using cryo-electron tomographyR35GM157116 · NIGMS · UNIVERSITY OF CHICAGO · PI MOHAMMED KAPLAN · 2025 to 2026
$820kDepartment of Education and Training | Australian Research Council (ARC) DP210100362Department of Education and Training | Australian Research Council (ARC) FT200100270National Health and Medical Research Council GNT2018980National Institute of Allergy and Infectious Diseases R01AI181213NIGMS NIH HHS R35 GM157116
6 · The paper itselfAbstract
IMPORTANCE: Dual membrane-spanning anti-sigma factors (Dma) are a novel class of regulatory proteins found solely among Bacteroidota. Previous studies demonstrated the importance of Dma1 in vesiculation, but the overall role of the Dma family in Bacteroides physiology remains poorly understood. Here, we show that Dma2 modulates vesiculation and the expression of select polysaccharide utilization loci (PULs) that target host-associated glycans
Indexed as
Bacterial Outer Membrane ProteinsBacterial ProteinsBacteroides thetaiotaomicronSigma FactorAnimalsGene Expression Regulation, BacterialMiceMutationProteomicsBacterial Outer Membrane ProteinsBacterial ProteinsSigma FactorbacteroidesgutOMVsPULsregulationsigma factorsvesicle
Identifiers
PMID41784630
PMCPMC13088901
What Socratic holds
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